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Nancy Thornberry is a world-renowned biochemist and an accomplished leader in the pharmaceutical industry, celebrated for her pivotal role in the discovery of transformative medicines. With over four decades of experience, she spent 30 years at Merck, where she led the research that resulted in the discovery of Januvia® (sitagliptin), a groundbreaking, first-in-class DPP-4 inhibitor for the treatment of type 2 diabetes. This drug became a multi-billion dollar blockbuster and significantly improved patient care worldwide. In 2015, she co-founded Kallyope, a biotechnology company focused on the gut-brain axis. As the founding CEO and Head of R&D, she was instrumental in building the company, pioneering its novel discovery platform, and advancing multiple therapeutic programs into clinical development. Her career is distinguished by a deep expertise in enzymology, drug discovery, and translating complex biological insights into life-changing therapies.
Nancy Thornberry's work history includes a series of influential roles in various companies. Here is a detailed list of his professional journey:
Led the research team at Merck that discovered Januvia®, a first-in-class DPP-4 inhibitor for treating type 2 diabetes. This blockbuster drug generated billions in revenue and established a new standard of care for millions of patients globally.
Co-founded and successfully led Kallyope, a pioneering biotechnology company focused on the gut-brain axis. She was instrumental in building the company, securing over $400 million in funding, and advancing multiple programs from discovery into clinical development.
In recognition of her distinguished and continuing achievements in original scientific research, she was elected as a member of the prestigious National Academy of Sciences in 2017, one of the highest honors for a scientist in the United States.
Honored with the Discoverers Award from the Pharmaceutical Research and Manufacturers of America in 2007 for her pioneering work in discovering Januvia®, recognizing the significant advancement it represented for patient care.
Named one of the "Fiercest Women in Life Sciences" by FiercePharma in 2018, acknowledging her influential leadership and groundbreaking contributions to the biopharmaceutical industry.
Muhlenberg College - Year 1975
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Kallyope is a New York-based biotechnology company that focuses on understanding and harnessing the gut-brain axis, the complex communication network between the gut and the brain. By leveraging its advanced technology platform, the company identifies novel targets and develops gut-restricted therapeutics to address a wide range of diseases, including metabolic disorders, central nervous system conditions, and inflammatory diseases, with the goal of creating safer and more effective treatments.
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