Mike Caponigro is a General Partner at Union Square Ventures (USV), a thesis-driven venture capital firm based in New York City. He brings a strong technical background to his investment work, having co-founded and served as the Chief Technology Officer of Flatiron Health. At Flatiron Health, he was instrumental in building the company's pioneering oncology data platform, which was ultimately acquired by Roche in 2018. Before Flatiron, Mike was a software engineer at Google, working on projects related to advertising and data infrastructure. His focus at USV often involves early-stage investments in companies leveraging data, networks, and novel technological approaches to solve significant problems, particularly in areas like healthcare, enterprise software, and data infrastructure.
Mike Caponigro's work history includes a series of influential roles in various companies. Here is a detailed list of his professional journey:
Co-founded Flatiron Health, a market-leading healthcare technology company focused on accelerating cancer research and improving patient care. As CTO, he led the engineering and product teams, building the technology platform that underpinned the company's success, leading to its acquisition by Roche for a reported $1.9 billion.
Elevated to General Partner at USV, a prominent venture capital firm known for early investments in companies like Twitter, Etsy, and Coinbase. In this role, he identifies, invests in, and supports transformative early-stage technology companies.
Contributed to key projects at Google, gaining valuable experience in large-scale software development and data systems prior to his entrepreneurial and investment career.
Western Illinois University
Highperformr Signals uncover buying intent and give you clear insights to target the right people at the right time — helping your sales, marketing, and GTM teams close more deals, faster.
1871 is a leading non-profit global technology and entrepreneurship center located in Chicago. It serves as an incubator for early-stage, high-growth digital startups, providing them with resources like workspace, mentorship, educational programming, access to capital, and a community of peers and industry experts. Housed in the Merchandise Mart, 1871 supports hundreds of startups and thousands of members in building and scaling their businesses.
Get verified emails, phone numbers, and LinkedIn profile details
Discover contacts with similar roles, seniority, or companies
Uncover insights like skills, work history, social links, and more
Explore contacts in-depth — from verified emails and phone numbers to LinkedIn activity, job changes, and more — all in one powerful view.
Highperformr AI helps you surface the right people and enrich your CRM with live, accurate contact insights so your teams can connect faster and close smarter.
Thousands of contacts — including decision-makers, influencers, and ICP matches — are just a search away.
Thousands of companies, including, are just a search away.