Kenneth A. Jacobson is a highly distinguished medicinal chemist and Chief of the Molecular Recognition Section in the Laboratory of Bioorganic Chemistry at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH). His extensive research career is dedicated to the study of G protein-coupled receptors (GPCRs), particularly purinergic receptors (adenosine and P2Y receptors). Dr. Jacobson's laboratory focuses on designing, synthesizing, and evaluating novel ligands (agonists, antagonists, and allosteric modulators) for these receptors. The ultimate goal is to understand their structure-activity relationships and develop new therapeutic agents for a variety of conditions, including pain, inflammation, cancer, thrombosis, and metabolic disorders. He is recognized globally for his prolific contributions to GPCR pharmacology, with over 1000 scientific publications and numerous patents that have significantly advanced the field and provided critical tools for researchers worldwide.
Kenneth A. Jacobson's work history includes a series of influential roles in various companies. Here is a detailed list of his professional journey:
Consistently ranked as a highly cited researcher in Pharmacology and Toxicology, indicating significant influence and contribution to the scientific community through his extensive body of published work (over 1000 papers).
Led groundbreaking research in the design and synthesis of selective ligands for adenosine and P2Y receptors, many of which are now standard pharmacological tools and have led to candidates for clinical development.
Recipient of the prestigious Goodman and Gilman Award in Receptor Pharmacology (2009) from the American Society for Pharmacology and Experimental Therapeutics (ASPET) for his outstanding contributions to the understanding of receptor pharmacology.
Co-inventor on a significant number of U.S. and international patents for novel chemical entities targeting GPCRs, highlighting the translational impact of his research in drug discovery.
Recognized with multiple NIH Director's Awards for his scientific achievements and leadership within the National Institutes of Health.
University of Washington - Year 1998
United States Military Academy at West Point - Year 1996
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