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Jon Stonehouse is the President and Chief Executive Officer of BioCryst Pharmaceuticals, a role he has held since 2007. With over three decades of experience in the biopharmaceutical industry, he has been instrumental in transforming BioCryst into a commercial-stage company dedicated to developing novel, oral, small-molecule medicines for rare diseases. Before joining BioCryst, Stonehouse served as Senior Vice President of Corporate Development at Merck KGaA, where he managed licensing, M&A, and strategic planning. His leadership at BioCryst is defined by a deep focus on patient needs, strategic financial management, and successfully guiding the company through critical clinical and regulatory milestones, most notably the global launch of ORLADEYO®.
Jon Stonehouse's work history includes a series of influential roles in various companies. Here is a detailed list of his professional journey:
Successfully guided BioCryst from a clinical-development company to a commercial-stage organization through the global launch of its flagship product, ORLADEYO® (berotralstat), for the treatment of hereditary angioedema (HAE).
Spearheaded major non-dilutive financing agreements, including a pivotal royalty financing deal, securing substantial capital to fund the company's research pipeline and commercial activities while protecting shareholder value.
Championed the strategic direction of the company to focus exclusively on developing oral medications for rare and serious diseases, significantly advancing the clinical pipeline, including promising candidates for complement-mediated diseases.
University of Minnesota-Twin Cities
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BioCryst Pharmaceuticals is a commercial-stage biotechnology company dedicated to discovering, developing, and commercializing novel, oral, small-molecule medicines for rare and serious diseases. Leveraging its expertise in structure-guided drug design, the company's primary focus is on oral therapies that can improve the lives of patients. Their flagship product, ORLADEYO® (berotralstat), is an oral, once-daily therapy for preventing attacks in patients with hereditary angioedema (HAE). BioCryst also developed and commercialized RAPIVAB® (peramivir injection) for the treatment of acute uncomplicated influenza.
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