David Roos
The Plains, Virginia,United States
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David Roos is a distinguished biologist and the E. Otis Kendall Professor of Biology at the University of Pennsylvania. He is renowned for his pioneering research in molecular parasitology, focusing on diseases like malaria and toxoplasmosis. Professor Roos has made significant contributions to the fields of genomics and bioinformatics, notably leading the development of influential pathogenomic database resources such as ToxoDB and PlasmoDB (part of VEuPathDB), which are vital tools for researchers worldwide. His laboratory investigates the cell and molecular biology of parasites, aiming to uncover mechanisms of infection and identify new therapeutic targets. He has also played key roles in directing genomics and computational biology initiatives, fostering interdisciplinary research and advancing our understanding of infectious diseases and broader biological systems.
Professional Summary
David Roos's work history includes a series of influential roles in various companies. Here is a detailed list of his professional journey:
Notable Achievements
Development of Eukaryotic Pathogen Databases (VEuPathDB)
Spearheaded the creation and ongoing development of the Eukaryotic Pathogen Genomics Database Resource (VEuPathDB), which includes highly successful components like PlasmoDB (for malaria parasites) and ToxoDB (for Toxoplasma gondii). These resources provide global access to integrated genomic, transcriptomic, proteomic, and other 'omic' data, profoundly impacting research on these important pathogens.
Pioneering Research in Apicomplexan Parasite Biology
Made significant breakthroughs in understanding the molecular biology, cell biology, and genomics of apicomplexan parasites, particularly *Toxoplasma gondii* and *Plasmodium falciparum*. His work has elucidated fundamental aspects of parasite invasion, replication, and differentiation, contributing to novel avenues for therapeutic interventions.
Leadership in Genomics and Computational Biology
Played a pivotal role in advancing genomics research and its application to infectious diseases. This includes serving as Director of the University of Pennsylvania Genomics Institute (now the Penn Center for Genome Integrity) and fostering collaborative, data-driven approaches to complex biological questions.
Elected Fellow of the American Association for the Advancement of Science (AAAS)
Recognized for his distinguished contributions to the field of biological sciences, particularly in molecular parasitology, genomics, and the development of impactful bioinformatics resources.
Elected Member of the National Academy of Sciences (NAS)
Elected in recognition of his distinguished and continuing achievements in original research in molecular parasitology and genomics.
Educational Background
BA Management, Business and Public Administration
Florida Atlantic University - Year 1980
Biology
University of Notre Dame - Year 1974
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Company Overview
Dynamics Research CorporationDynamics Research Corporation (DRC) was a U.S. based company providing technology, engineering, and information solutions primarily to federal and state governments. Key areas of focus included national security, defense, intelligence, and healthcare. DRC offered services in systems engineering, information technology, logistics, and test and evaluation. The company was acquired by Engility Holdings, Inc. in January 2014, which itself was later acquired by Science Applications International Corporation (SAIC) in 2019. Therefore, DRC no longer operates as an independent entity.
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