Carl Anfenson
Arlington Heights, Illinois,United States
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Carl Anfenson (referring to Christian Boehmer Anfinsen Jr.) was a distinguished American biochemist renowned for his pioneering work on the relationship between the amino acid sequence of a protein and its biologically active conformation. His research primarily focused on the enzyme ribonuclease, leading to the formulation of 'Anfinsen's dogma,' which postulates that the three-dimensional structure of a native protein in its normal physiological milieu is the one in which the Gibbs free energy of the whole system is lowest; that is, that the native conformation is determined by the totality of interatomic interactions and hence by the amino acid sequence, in a given environment. He held prominent positions at institutions like the National Institutes of Health (NIH) and Johns Hopkins University, significantly advancing the field of molecular biology.
Professional Summary
Carl Anfenson's work history includes a series of influential roles in various companies. Here is a detailed list of his professional journey:
Notable Achievements
Nobel Prize in Chemistry (1972)
Shared the Nobel Prize for his fundamental research on ribonuclease, especially concerning the connection between the amino acid sequence and the biologically active conformation. This work established that the primary structure (amino acid sequence) of a protein dictates its tertiary structure (three-dimensional shape).
Anfinsen's Dogma (Thermodynamic Hypothesis)
A groundbreaking principle stating that, at least for small globular proteins, the native structure is determined solely by the protein's amino acid sequence. This implies that the information required to fold the protein into its specific 3D shape is encoded within its sequence.
Elected to the National Academy of Sciences (1963)
Recognized for his distinguished and continuing achievements in original scientific research in biochemistry.
Work at the National Institutes of Health (NIH)
Served as Chief of the Laboratory of Chemical Biology at the National Institute of Arthritis, Metabolism and Digestive Diseases (NIAMDD) at NIH, where much of his Nobel-winning research was conducted.
Professor of Biology at Johns Hopkins University
Later in his career, he joined Johns Hopkins University as a professor, continuing his research and mentorship in protein chemistry.
Educational Background
The University of Chicago Booth School of Business - Year 1999
Indiana University Bloomington - Year 1986
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Company Overview
Old Second National BankOld Second National Bank is a community bank headquartered in Aurora, Illinois, with a rich history dating back to 1871. It provides a wide range of banking services to individuals, businesses, and governmental entities across the Chicago metropolitan area and surrounding communities. Services include personal and business checking and savings accounts, loans (commercial, mortgage, consumer), treasury management, and wealth management solutions. Old Second is committed to local decision-making and community involvement, striving to be the preferred financial partner for its customers.
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