What Does Vtesse Do?

Total employees35
HeadquartersGaithersburg
Founded2013

Vtesse, Inc. was a clinical-stage biopharmaceutical company focused on the development of drugs for patients suffering from Niemann-Pick Type C1 disease (NPC1) and other rare, severe, life-threatening diseases. Its lead product candidate was VTS-270 (a specific composition of 2-hydroxypropyl-β-cyclodextrin), aimed at treating the neurological manifestations of NPC1. Vtesse was launched in 2013 by Cydan Development, Inc., an orphan drug accelerator. The company made significant progress, including receiving FDA Breakthrough Therapy Designation for VTS-270. Vtesse was acquired by Sucampo Pharmaceuticals in April 2017. Sucampo was subsequently acquired by Mallinckrodt in February 2018. The rights to VTS-270 (later known as Adrabetadex) were then acquired by Mandos LLC from Mallinckrodt in 2021.

Where Is Vtesse's Headquarters?

Vtesse officeVtesse officeVtesse officeVtesse office
*Images sourced via web search. Rights belong to original owners

HQ Function

Served as the main center for Vtesse's clinical development programs, regulatory affairs, scientific research management, and corporate operations focused on rare diseases.

Notable Features:

As a clinical-stage company incubated within a larger development group's facilities, its headquarters likely comprised modern office and lab-support spaces designed for managing clinical trials and R&D collaborations, rather than large-scale manufacturing capabilities.

Work Culture:

The work culture at Vtesse was likely driven by a strong patient-centric mission, typical of rare disease biotechs. It would have emphasized scientific innovation, collaboration, and a sense of urgency to address critical unmet medical needs for NPC1 patients and their families.

HQ Significance:

The Gaithersburg, Maryland location provided Vtesse with proximity to key U.S. regulatory agencies like the FDA, a rich talent pool in biotechnology, and a network of research institutions, which was advantageous for its drug development efforts.

Values Reflected in HQ: The headquarters would have reflected Vtesse's commitment to advancing science for rare diseases, fostering innovation, and maintaining a lean, focused operational model to expedite development.

Location:

During its operational phase, Vtesse's global presence was primarily defined by its international Phase 2b/3 clinical trial program for VTS-270. The company collaborated with leading medical centers and investigators in multiple countries, including the United States, United Kingdom, Germany, France, Spain, Turkey, and Australia, to enroll and treat patients with Niemann-Pick Type C1 disease. This global reach was essential for studying a rare disease with a dispersed patient population.

Street Address:

200 Orchard Ridge Drive, Suite 150

City:

Gaithersburg

State/Province:

Maryland

Country:

USA

Where Else Does Vtesse Operate Around the World?

Cambridge, Massachusetts, USA

Address: One Main Street, Suite 1420, Cambridge, MA 02142 (Cydan Development HQ)

Served as a strategic hub for incubation, corporate development, and access to a leading biotech innovation cluster via its parent company, Cydan Development.

Buying Intent Signals for Vtesse

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Vtesse? Meet the Executive Team

As of April 2025, Vtesse' leadership includes:

Dr. Ben Machielse - Former President and Chief Executive Officer
Dr. Kevin M. Bax - Former Chief Business Officer (also affiliated with Cydan Development)
Dr. Kevin Johnson - Former Senior Vice President, Development

Who's Investing in Vtesse?

Vtesse has been backed by several prominent investors over the years, including:

Cydan Development, Inc. (Founding Accelerator)
New Enterprise Associates (NEA) (via Cydan)
Pfizer Venture Investments (via Cydan)
Lundbeckfond Ventures (via Cydan)
Longitude Capital (via Cydan)
Alexandria Venture Investments (via Cydan)
National Niemann-Pick Disease Foundation (Grant Funder & Advocacy Partner)
Ara Parseghian Medical Research Foundation (Grant Funder & Advocacy Partner)

What Leadership Changes Has Vtesse Seen Recently?

Hire0
Exits0

Vtesse, Inc. was acquired by Sucampo Pharmaceuticals in 2017 and its assets subsequently became part of Mallinckrodt in 2018. Vtesse no longer operates as an independent entity. Therefore, there have been no executive new hires or exits directly attributable to 'Vtesse' as a standalone company in the last 12 months. Leadership changes concerning its former lead product, Adrabetadex (VTS-270), would occur within Mandos LLC, the current rights holder.

What Technology (Tech Stack) Is Used byVtesse?

Discover the tools Vtesse uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Vtesse Email Formats and Examples

Based on common practices for biopharmaceutical companies of its size and era, Vtesse likely utilized standard professional email formats. The exact historical format is not publicly confirmed post-acquisition, as the company no longer operates independently.

[first_initial][last]@vtessepharma.com

Format

jdoe@vtessepharma.com (illustrative example)

Example

70%

Success rate

What's the Latest News About Vtesse?

PR Newswire • April 11, 2017

Sucampo to Acquire Vtesse, Further Diversifying Orphan Disease Pipeline with Late-Stage Candidate for Niemann-Pick Disease Type C1

Sucampo Pharmaceuticals, Inc. announced it had entered into a definitive agreement to acquire Vtesse, Inc. for $200 million plus potential milestones. The acquisition centered on Vtesse's lead product candidate, VTS-270, for Niemann-Pick Type C1 (NPC1) disease, aiming to strengthen Sucampo's focus on specialized and orphan diseases....more

PR Newswire • January 7, 2015

Vtesse, Inc. Receives FDA Breakthrough Therapy Designation for VTS-270 for Niemann-Pick Type C1 Disease

Vtesse, Inc. announced that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for VTS-270, its investigational drug for Niemann-Pick Type C1 disease (NPC). This designation was intended to expedite the development and review of VTS-270 for this serious and life-threatening condition....more

PR Newswire • October 3, 2016

Vtesse, Inc. Announces First Patient Enrolled in Pivotal Phase 2b/3 Clinical Trial of VTS-270 for Treatment of Niemann-Pick Type C1 Disease

Vtesse announced the enrollment of the first patient in its pivotal Phase 2b/3 clinical trial of VTS-270. The global, prospective, randomized, double-blind, sham-controlled study aimed to assess the efficacy and safety of VTS-270 in children with NPC1 disease....more

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