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The U.S. Chamber of Commerce is the world's largest business federation representing the interests of more than 3 million businesses of all sizes, sectors, and regions, as well as state and local chambers and industry associations. The Chamber is dedicated to advancing human progress through an economic, political and social system based on free enterprise, incentives, individual initiative and responsibility. They advocate for pro-business policies that create jobs and grow the U.S. economy.
Serves as the primary hub for the organization's advocacy efforts, policy development, member relations, events, and administrative operations.
A historic landmark building known for its neoclassical architecture. It houses the American Business History Center, event spaces like the Hall of Flags, and modern broadcast studios (e.g., Holliday C. Homrich III Studio).
Professional, policy-driven, and dynamic, focused on advocating for American businesses. The environment is characterized by expertise in public policy, government affairs, and a strong emphasis on networking and influencing legislative outcomes.
Its prime location in the nation's capital allows for direct engagement with policymakers, government officials, and diplomats. The building itself is a symbol of American enterprise and a frequent site for significant policy discussions and announcements.
While headquartered in the U.S., the U.S. Chamber of Commerce has a significant global impact through its International Affairs Division. It advocates for international trade and investment policies that benefit American businesses. It engages with foreign governments, international organizations, and American Chambers of Commerce (AmChams) abroad. The Chamber also operates several bilateral business councils (e.g., U.S.-India Business Council, U.S.-Africa Business Center) to foster economic ties with specific countries and regions. They do not typically operate physical branch offices internationally in the same way a multinational corporation would, but rather exert influence through policy, partnerships, and representative missions.
1615 H St NW
Washington
D.C.
USA
Address: While not a large physical branch, the Chamber has regional staff and offices, e.g., the Great Lakes Regional Office. Specific public-facing addresses for these are often not listed; representation is through regional VPs.
To extend the Chamber's national advocacy efforts to a regional level, ensuring local business voices are heard and that members are informed about federal policies impacting their area.
Address: The U.S. Chamber maintains a network of regional outreach managers and senior executives who work remotely or from smaller, non-public-facing offices across the country to engage with local business communities and stakeholders.
To provide a widespread presence and direct points of contact for businesses and local chambers throughout the United States, ensuring a broad base of support and input for national policy positions.
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As of April 2025, U.S. Chamber of Commerce' leadership includes:
U.S. Chamber of Commerce has been backed by several prominent investors over the years, including:
The U.S. Chamber of Commerce has seen some key leadership transitions and appointments to strengthen its policy and advocacy teams. Notable changes often involve strategic roles in international affairs and technology policy.
Discover the tools U.S. Chamber of Commerce uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
The U.S. Chamber of Commerce commonly uses the first initial followed by the last name for its email addresses. This is a standard format for many large organizations.
flast@uschamber.com
Format
sclark@uschamber.com
Example
85%
Success rate
U.S. Chamber of Commerce Official Website • May 21, 2024
The U.S. Chamber of Commerce's Center for Capital Markets Competitiveness (CCMC) issued a statement on the SEC's final rules regarding the U.S. Treasury market, expressing concerns about the potential impact of mandatory clearing on market liquidity and costs....more
U.S. Chamber of Commerce Official Website • May 20, 2024
The U.S. Chamber released a statement regarding the joint agency guidance on Section 8 of the Real Estate Settlement Procedures Act (RESPA), highlighting its importance for transparency and consumer protection in real estate transactions....more
Reuters • May 15, 2024
The U.S. Chamber of Commerce, along with other business groups, is involved in ongoing legal action challenging California's fast food worker law (AB 1228), which raises the minimum wage for fast food workers and establishes a council to set wage and working conditions. The groups argue the law is harmful to businesses and franchisees....more
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