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Two Sigma Ventures is an early-stage venture capital firm that partners with visionary entrepreneurs leveraging data science, artificial intelligence (AI), machine learning, and advanced computing to create transformative businesses. They provide capital, strategic guidance, and access to the broader Two Sigma ecosystem, which includes deep expertise in technology and quantitative analysis. Their focus areas typically include fintech, enterprise software, biotech, and other sectors where data-driven approaches can create significant value.
Serves as the central hub for investment activities, portfolio company support, operations, and collaboration with the broader Two Sigma organization.
State-of-the-art facilities with advanced technology infrastructure, collaborative workspaces designed to foster innovation, and access to Two Sigma's extensive resources.
Characterized by intellectual curiosity, a data-driven approach to decision-making, collaboration, and a strong emphasis on technological innovation. The culture encourages rigorous analysis and supporting entrepreneurs.
Its New York City location places it at the nexus of finance and technology, providing strategic advantages for deal sourcing, talent acquisition, and industry partnerships.
While its primary offices are in New York and San Francisco, Two Sigma Ventures invests in companies globally. Its team actively scouts for and supports innovative startups across North America, Europe, and other key international markets, leveraging Two Sigma's global network and data science capabilities to identify and nurture promising ventures worldwide.
100 Avenue of the Americas
New York
NY
USA
Address: Specific address not publicly detailed, likely a presence within a Two Sigma office or strategic co-working space.
To maintain a strong connection with the West Coast's innovation hub, access deal flow, and provide localized support to startups in the region.
Address: Specific address not publicly detailed for Ventures, likely leveraging Two Sigma's London office.
To expand global reach, tap into European innovation, and support portfolio companies with international ambitions.
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As of April 2025, Two Sigma Ventures' leadership includes:
Two Sigma Ventures has been backed by several prominent investors over the years, including:
As a private venture capital firm, detailed executive transitions are not always publicly announced unless significant. Recent public information indicates a stable core leadership team, with any team growth likely supporting their new fund deployment.
Discover the tools Two Sigma Ventures uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
Two Sigma Ventures likely follows common professional email formats, often incorporating the first name, last name, or initials. The domain is @twosigmaventures.com.
[first].[last]@twosigmaventures.com or [first_initial][last]@twosigmaventures.com
Format
jane.doe@twosigmaventures.com
Example
80%
Success rate
PRNewswire • May 10, 2023
Two Sigma Ventures announced the first and final close of two new venture capital funds totaling $400 million in aggregate commitments. The new funds will enable Two Sigma Ventures to continue to invest with a distinctive model that leverages Two Sigma's broader platform, data science expertise, and resources to support founders from inception through growth stages....more
Two Sigma Ventures Blog • February 7, 2024
A blog post from Partner Addie Lerner discussing 'Era Retrospectives,' a framework for founders to navigate pivotal company moments, reflecting Two Sigma Ventures' commitment to providing deep, strategic support to its portfolio companies....more
Forbes • November 15, 2023
Hadrian, a company building the future of advanced manufacturing, backed by Two Sigma Ventures, was featured in Forbes' AI 50 list, highlighting the firm's investment in impactful AI-driven companies....more
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