What Does Tripos Do?

Total employees250
HeadquartersSt. Louis
Founded1979

Tripos, Inc. was a leading provider of drug discovery chemistry software and services for the life sciences industry. Founded in 1979, its flagship product, SYBYL, became a cornerstone for molecular modeling, simulation, and informatics. Tripos offered a suite of tools for QSAR, pharmacophore modeling, combinatorial chemistry, and data management, significantly aiding pharmaceutical and biotechnology companies in their research and development efforts. In 2007, Tripos was acquired by Vector Capital, and subsequently, in 2014, key software assets including the SYBYL line were acquired by Certara, where its technologies continue to be developed and integrated into Certara's broader portfolio of modeling and simulation solutions.

Where Is Tripos's Headquarters?

Tripos officeTripos officeTripos officeTripos office
*Images sourced via web search. Rights belong to original owners

HQ Function

Served as the global headquarters, housing research and development, software engineering, sales, marketing, customer support, and corporate administration.

Notable Features:

Likely a corporate office environment with facilities tailored for software development, scientific research collaboration, and customer training.

Work Culture:

Characterized by a strong focus on scientific innovation, computational chemistry, and software excellence, fostering a collaborative environment for scientists and engineers dedicated to advancing drug discovery.

HQ Significance:

The St. Louis headquarters was pivotal for the development and global distribution of Tripos's influential SYBYL software suite and other informatics tools.

Values Reflected in HQ: Innovation in scientific software, commitment to advancing pharmaceutical research, and customer-centric support for the life sciences community.

Location:

Historically, Tripos supported global pharmaceutical, biotechnology, and academic research institutions with its software solutions. This included direct sales operations, technical support teams, training services, and scientific collaborations across North America, Europe (notably UK, Germany, France), and parts of Asia (e.g., Japan via distributors). Its software was used by researchers worldwide to accelerate drug discovery and development.

Street Address:

1699 South Hanley Road

City:

St. Louis

State/Province:

Missouri

Country:

USA

Where Else Does Tripos Operate Around the World?

Basingstoke, Hampshire, UK

Address: Unknown exact street address (historical)

To support the significant pharmaceutical and biotechnology research presence in Europe, offering localized expertise and services for Tripos's software solutions.

Munich, Germany

Address: Unknown exact street address (historical)

Catered to the strong German chemical, pharmaceutical, and biotech industries, providing direct access to Tripos's tools and expertise.

Buying Intent Signals for Tripos

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Tripos? Meet the Executive Team

As of April 2025, Tripos' leadership includes:

Dr. John P. McAlister, Jr. - Former President and CEO
Dr. Trevor W. Heritage - Former Senior Vice President, R&D and Chief Scientific Officer
Patrick Fromal - Former Chief Financial Officer

Who's Investing in Tripos?

Tripos has been backed by several prominent investors over the years, including:

Vector Capital (Acquired Tripos in 2007)
Previously publicly traded (NASDAQ: TRPS) before Vector Capital acquisition

What Leadership Changes Has Tripos Seen Recently?

Hire0
Exits0

As Tripos was acquired by Vector Capital in 2007 and its key assets later by Certara in 2014, executive team changes primarily occurred around these acquisition events. Specific hires/exits in the 'last 12 months' are not applicable as Tripos no longer operates as an independent entity. Historical news would reflect leadership during its operational years and transitions during acquisitions.

Departures

N/A, No executive departures in the last 12 months as Tripos is now part of Certara.

New Appointments:

N/A, No new executive appointments in the last 12 months as Tripos is now part of Certara.

What Technology (Tech Stack) Is Used byTripos?

Discover the tools Tripos uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Tripos Email Formats and Examples

Historically, Tripos, Inc. likely used common corporate email formats such as [first_initial][last]@tripos.com or [first].[last]@tripos.com. As the company's assets are now part of Certara, any current business communication would use Certara's email formats.

[first_initial][last]@tripos.com (historical)

Format

jdoe@tripos.com (historical example)

Example

0 (The tripos.com domain is no longer actively used for new email communication by the original entity; it may redirect or be inactive. Communication is via Certara.)%

Success rate

What's the Latest News About Tripos?

Certara Press ReleaseAugust 1, 2014

Certara Acquires Tripos Discovery Informatics Business from Vector Capital Portfolio Company

Certara announced its acquisition of the Tripos Discovery Informatics business, including the SYBYL software suite, from a Vector Capital portfolio company. This strategic acquisition aimed to enhance Certara's portfolio with leading molecular modeling and cheminformatics tools....more

St. Louis Business Journal / PR NewswireFebruary 20, 2007

Vector Capital to acquire Tripos for $47M

Tripos Inc. announced it agreed to be acquired by private equity firm Vector Capital in a deal valued at approximately $47 million. The acquisition aimed to take Tripos private and support its growth strategies in the scientific software market....more

Tripos Press Release (via FierceBiotech or similar archive)October 25, 2004

Tripos Launches New SYBYL Upgrade (SYBYL 7.0)

Tripos announced the release of SYBYL 7.0, a significant upgrade to its flagship molecular modeling environment. The new version included enhancements in usability, 3D QSAR, protein modeling, and informatics, further solidifying its position in the drug discovery software market....more

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