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Tripos, Inc. was a leading provider of drug discovery chemistry software and services for the life sciences industry. Founded in 1979, its flagship product, SYBYL, became a cornerstone for molecular modeling, simulation, and informatics. Tripos offered a suite of tools for QSAR, pharmacophore modeling, combinatorial chemistry, and data management, significantly aiding pharmaceutical and biotechnology companies in their research and development efforts. In 2007, Tripos was acquired by Vector Capital, and subsequently, in 2014, key software assets including the SYBYL line were acquired by Certara, where its technologies continue to be developed and integrated into Certara's broader portfolio of modeling and simulation solutions.
Served as the global headquarters, housing research and development, software engineering, sales, marketing, customer support, and corporate administration.
Likely a corporate office environment with facilities tailored for software development, scientific research collaboration, and customer training.
Characterized by a strong focus on scientific innovation, computational chemistry, and software excellence, fostering a collaborative environment for scientists and engineers dedicated to advancing drug discovery.
The St. Louis headquarters was pivotal for the development and global distribution of Tripos's influential SYBYL software suite and other informatics tools.
Historically, Tripos supported global pharmaceutical, biotechnology, and academic research institutions with its software solutions. This included direct sales operations, technical support teams, training services, and scientific collaborations across North America, Europe (notably UK, Germany, France), and parts of Asia (e.g., Japan via distributors). Its software was used by researchers worldwide to accelerate drug discovery and development.
1699 South Hanley Road
St. Louis
Missouri
USA
Address: Unknown exact street address (historical)
To support the significant pharmaceutical and biotechnology research presence in Europe, offering localized expertise and services for Tripos's software solutions.
Address: Unknown exact street address (historical)
Catered to the strong German chemical, pharmaceutical, and biotech industries, providing direct access to Tripos's tools and expertise.
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As of April 2025, Tripos' leadership includes:
Tripos has been backed by several prominent investors over the years, including:
As Tripos was acquired by Vector Capital in 2007 and its key assets later by Certara in 2014, executive team changes primarily occurred around these acquisition events. Specific hires/exits in the 'last 12 months' are not applicable as Tripos no longer operates as an independent entity. Historical news would reflect leadership during its operational years and transitions during acquisitions.
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Historically, Tripos, Inc. likely used common corporate email formats such as [first_initial][last]@tripos.com or [first].[last]@tripos.com. As the company's assets are now part of Certara, any current business communication would use Certara's email formats.
[first_initial][last]@tripos.com (historical)
Format
jdoe@tripos.com (historical example)
Example
0 (The tripos.com domain is no longer actively used for new email communication by the original entity; it may redirect or be inactive. Communication is via Certara.)%
Success rate
Certara Press Release • August 1, 2014
Certara announced its acquisition of the Tripos Discovery Informatics business, including the SYBYL software suite, from a Vector Capital portfolio company. This strategic acquisition aimed to enhance Certara's portfolio with leading molecular modeling and cheminformatics tools....more
St. Louis Business Journal / PR Newswire • February 20, 2007
Tripos Inc. announced it agreed to be acquired by private equity firm Vector Capital in a deal valued at approximately $47 million. The acquisition aimed to take Tripos private and support its growth strategies in the scientific software market....more
Tripos Press Release (via FierceBiotech or similar archive) • October 25, 2004
Tripos announced the release of SYBYL 7.0, a significant upgrade to its flagship molecular modeling environment. The new version included enhancements in usability, 3D QSAR, protein modeling, and informatics, further solidifying its position in the drug discovery software market....more
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