What Does Triplet Therapeutics Do?

Total employees60
HeadquartersCambridge
Founded2018

Triplet Therapeutics was a biotechnology company founded in 2018, dedicated to developing transformative treatments for repeat expansion disorders (REDs), with an initial focus on Huntington's disease. The company aimed to address the underlying genetic cause of these debilitating conditions by developing antisense oligonucleotides (ASOs). Despite raising significant funding, including a $59 million Series A round, and advancing its lead candidate, TTX-3360, into Phase Ib/IIa clinical trials, Triplet Therapeutics ceased operations in late 2022 after the program did not meet its primary objectives.

Where Is Triplet Therapeutics's Headquarters?

Triplet Therapeutics officeTriplet Therapeutics officeTriplet Therapeutics officeTriplet Therapeutics office
*Images sourced via web search. Rights belong to original owners

HQ Function

Formerly served as the primary site for research and development, clinical operations, and corporate functions.

Notable Features:

Located in the Kendall Square biotech hub, likely utilizing modern lab and office spaces typical for research-intensive companies in a state-of-the-art life sciences building.

Work Culture:

Historically fostered a science-driven, innovative, and collaborative environment focused on addressing urgent patient needs in neurodegenerative diseases. The team was dedicated to pioneering approaches for genetically defined disorders.

HQ Significance:

Its Cambridge location provided strategic access to a rich ecosystem of top-tier talent, world-class research institutions, and potential collaborators within the life sciences sector.

Values Reflected in HQ: The choice of a state-of-the-art facility in a leading biotech cluster like Kendall Square reflected its commitment to cutting-edge science, innovation, and attracting the best minds to tackle complex diseases.

Location:

As a US-based biotechnology company, Triplet Therapeutics's core operations, including research, development, and corporate functions, were primarily centered in the United States. While its research into repeat expansion disorders had global implications for patient populations worldwide, and clinical trials may have involved international sites, its physical operational presence was concentrated domestically in Cambridge, MA.

Street Address:

225 Binney Street

City:

Cambridge

State/Province:

MA

Country:

USA

Where Else Does Triplet Therapeutics Operate Around the World?

No additional office locations available.

Buying Intent Signals for Triplet Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Triplet Therapeutics? Meet the Executive Team

As of April 2025, Triplet Therapeutics' leadership includes:

Nessan Bermingham, Ph.D. - Co-founder, Former President and CEO, Former Executive Chair
Alan Buckler, Ph.D. - Co-founder and Former Chief Scientific Officer
Irina Antonijevic, M.D., Ph.D. - Former Chief Medical Officer
Lisa M. Olson, Ph.D. - Former Chief Scientific Officer (succeeded Alan Buckler)
Bryan J. Stuart - Former Chief Operating Officer

Who's Investing in Triplet Therapeutics?

Triplet Therapeutics has been backed by several prominent investors over the years, including:

Atlas Venture
MPM Capital
Pfizer Ventures
Lightstone Ventures
Omega Funds
Gurnet Point Capital
Alexandria Venture Investments
Casdin Capital
Tekla Capital Management LLC

What Leadership Changes Has Triplet Therapeutics Seen Recently?

Hire0
Exits0

Triplet Therapeutics ceased operations in late 2022. Consequently, there have been no executive new hires or exits in the last 12 months (from early 2023 to early 2024). All executive roles concluded with the company's wind-down procedures.

What Technology (Tech Stack) Is Used byTriplet Therapeutics?

Discover the tools Triplet Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Triplet Therapeutics Email Formats and Examples

While Triplet Therapeutics is no longer operational, biotechnology companies of its nature commonly use email formats such as [first_initial][last]@[companydomain].com or [first].[last]@[companydomain].com. These are speculative based on common industry practices.

[first_initial][last]@triplettherapeutics.com (e.g., jdoe@triplettherapeutics.com) or [first].[last]@triplettherapeutics.com (e.g., jane.doe@triplettherapeutics.com)

Format

asmith@triplettherapeutics.com (example of a plausible historical format)

Example

0%

Success rate

What's the Latest News About Triplet Therapeutics?

Endpoints News • November 30, 2022

Triplet Therapeutics winds down after failing to hit PhIb goals for Huntington's drug

Triplet Therapeutics announced it was ceasing operations after its lead candidate, TTX-3360, for Huntington's disease did not meet its objectives in a Phase Ib/IIa clinical trial. The company had been developing therapies for repeat expansion disorders....more

Fierce Biotech (reporting on PR Newswire release) • December 10, 2019

Triplet Therapeutics Launches with $59 Million in Seed and Series A Financing to Develop Novel Treatments for Repeat Expansion Disorders

Triplet Therapeutics officially launched with a combined $59 million in Seed and Series A financing. The round was co-led by MPM Capital and Atlas Venture, with significant participation from Pfizer Ventures, Lightstone Ventures, Omega Funds, Gurnet Point Capital, and Alexandria Venture Investments. The company aimed to address the underlying cause of repeat expansion disorders, with an initial focus on Huntington's disease....more

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