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Tigenix
What Does Tigenix Do?
Tigenix NV was a European biopharmaceutical company at the forefront of developing and commercializing novel cell therapies to address serious medical conditions. Its flagship product, Alofisel (darvadstrocel), was the first allogeneic stem cell therapy to receive central marketing authorization in Europe for treating complex perianal fistulas in adult Crohn's disease patients. Tigenix utilized its proprietary platform of allogeneic expanded adipose-derived stem cells (eASCs) to develop treatments for inflammatory and autoimmune diseases. In July 2018, Tigenix was acquired by Takeda Pharmaceutical Company Limited, integrating its assets and expertise into Takeda's global gastroenterology R&D.
Where Is Tigenix's Headquarters?
HQ Function
The headquarters served as the central hub for Tigenix's research and development, clinical operations, corporate management, and strategic planning before its acquisition by Takeda.
Notable Features:
The Leuven site likely housed advanced laboratory facilities for stem cell research, process development, quality control, and corporate offices managing global clinical trials and regulatory affairs.
Work Culture:
As a clinical-stage biopharmaceutical innovator, Tigenix likely fostered a dynamic, science-driven work culture focused on cutting-edge cell therapy research, rigorous clinical development, and bringing novel treatments to patients. Collaboration across research, clinical, and manufacturing teams was essential.
HQ Significance:
The Leuven headquarters was the nerve center for Tigenix's pioneering work in allogeneic stem cell therapies, leading to the development and European approval of Alofisel, a landmark achievement in regenerative medicine.
Values Reflected in HQ: The headquarters would have embodied Tigenix's commitment to scientific innovation, patient-centricity, high-quality research, and a pioneering spirit in the field of advanced therapies.
Location:
Prior to its acquisition, Tigenix had a strong European footprint, with R&D headquarters in Belgium and manufacturing operations in Spain. The company focused on securing regulatory approvals and commercializing its cell therapies in Europe, with Alofisel approved by the European Commission. It was also actively exploring pathways for market entry in other key regions, including the United States.
Street Address:
Romeinse straat 12, bus 2
City:
Leuven
State/Province:
Flemish Brabant
Country:
Belgium
Where Else Does Tigenix Operate Around the World?
Madrid, Spain
Address: Calle Marconi, 1, Parque TecnolĂłgico de Madrid, 28760 Tres Cantos, Madrid, Spain
Served as the primary manufacturing site for Alofisel and supported clinical and commercial operations in Spain and other parts of Europe.
Buying Intent Signals for Tigenix
Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.
Who's Leading Tigenix? Meet the Executive Team
As of April 2025, Tigenix' leadership includes:
Who's Investing in Tigenix?
Tigenix has been backed by several prominent investors over the years, including:
What Leadership Changes Has Tigenix Seen Recently?
The most significant executive event for Tigenix was its acquisition by Takeda Pharmaceutical Company Limited, announced in early 2018 and completed in July 2018. This led to the transition and departure of Tigenix's existing executive team as the company and its operations were integrated into Takeda. There were no publicly noted major hires to Tigenix's independent executive team in the immediate 12 months leading up to the finalized acquisition.
Departures
New Appointments:
What Technology (Tech Stack) Is Used byTigenix?
Discover the tools Tigenix uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
Tigenix Email Formats and Examples
Prior to its acquisition by Takeda in 2018, Tigenix likely utilized a standard corporate email format. Common formats included first initial followed by last name, or first name separated by a dot from the last name. As Tigenix is now fully integrated into Takeda, the tigenix.com email domain is no longer in active use for new communications.
[first].[last]@tigenix.com
Format
john.doe@tigenix.com
Example
0%
Success rate
What's the Latest News About Tigenix?
European Medicines Agency (EMA) / Company Press Release • March 23, 2018
Tigenix's Alofisel (darvadstrocel) Receives European Commission Marketing Authorisation for Complex Perianal Fistulas in Crohn's Disease
The European Commission granted marketing authorisation for Alofisel (darvadstrocel) for the treatment of complex perianal fistulas in adult patients with non-active/mildly active luminal Crohn's disease. This marked Alofisel as the first allogeneic stem cell therapy to receive central marketing authorisation in Europe....more
Takeda Pharmaceutical Company Limited • July 18, 2018
Takeda Completes Acquisition of TiGenix
Takeda Pharmaceutical Company Limited announced the successful completion of its acquisition of Tigenix NV. This acquisition aimed to enhance Takeda's late-stage GI pipeline and expand its presence in specialty medicines, particularly with the addition of Alofisel....more
Tigenix / Takeda Press Release • January 5, 2018
Takeda Announces Voluntary Conditional Takeover Bid for TiGenix to Acquire Alofisel
Takeda Pharmaceutical Company Limited announced its intention to launch a voluntary public takeover bid for Tigenix NV for EUR 1.78 per share, valuing Tigenix at approximately EUR 520 million. The move was aimed at acquiring Alofisel and strengthening Takeda's leadership in gastroenterology....more
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