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Third Rock Ventures is a life sciences venture capital firm focused on building transformative companies that can dramatically improve the lives of patients. They partner with entrepreneurs and academic innovators to translate groundbreaking scientific discoveries into new medicines and healthcare solutions. Their approach typically involves early-stage investment, active company building, and a deep commitment to scientific rigor and patient impact. They invest across various therapeutic areas including oncology, immunology, neurology, and rare diseases, often creating companies from scratch based on compelling science.
The Boston headquarters serves as the central operational hub, driving investment strategy, deal sourcing, portfolio company incubation and support, and overall firm management.
Located in the Seaport District, a dynamic and modern area of Boston. The office is designed to foster collaboration and innovation, with modern amenities and meeting spaces for its team and portfolio companies.
The work culture at Third Rock Ventures is characterized by a fast-paced, intellectually stimulating, and collaborative environment. There is a strong emphasis on scientific excellence, entrepreneurial spirit, and a shared mission to make a significant impact on human health.
Boston's dense ecosystem of world-class academic institutions, research hospitals, and a vibrant biotech industry provides Third Rock Ventures with unparalleled access to cutting-edge science, talent, and co-investment opportunities.
While Third Rock Ventures's physical offices are in the United States (Boston and San Francisco), its investment scope and the operations of its portfolio companies are often global. They scout for innovation internationally and their portfolio companies frequently conduct clinical trials, form partnerships, and aim to commercialize therapies on a global scale. Their network of scientific advisors and collaborators also has an international reach.
200 Pier 4 Boulevard, 4th Floor
Boston
MA
USA
Address: One Letterman Drive, Building C, Suite C3-300, San Francisco, CA 94129
To leverage the significant concentration of scientific innovation, talent, and academic research institutions on the West Coast, complementing its East Coast operations and providing broader geographical coverage for new opportunities.
Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.
As of April 2025, Third Rock Ventures' leadership includes:
Third Rock Ventures has been backed by several prominent investors over the years, including:
In the past year, Third Rock Ventures has made significant additions and promotions to its team, strengthening its leadership in investment, finance, and human resources.
Discover the tools Third Rock Ventures uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
Third Rock Ventures commonly uses the email format combining the first initial and last name. This is a frequent pattern among venture capital and life science firms.
[first_initial][last]@thirdrockventures.com
Format
rTepper@thirdrockventures.com
Example
85%
Success rate
Third Rock Ventures • May 2, 2023
Third Rock Ventures announced several key appointments and promotions, including Lorence Kim, M.D., as Venture Partner, Kush M. Parmar, M.D., Ph.D., as Managing Director, Jeffrey M. D’Amelia as Chief Financial Officer, and Mary-Alice Miller as Chief Human Resources Officer, strengthening its team to drive future growth and innovation....more
Third Rock Ventures • March 28, 2023
Third Rock Ventures successfully closed its sixth fund, Fund VI, raising $1.1 billion. The fund will enable the firm to continue its strategy of discovering, launching, and building innovative life sciences companies focused on addressing significant unmet medical needs....more
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