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The Engine, built by MIT, is a venture capital firm dedicated to investing in and supporting early-stage Tough Tech companies. These are startups founded on breakthrough science and engineering with the potential to address critical global challenges such as climate change, human health, and advanced infrastructure. The Engine provides not only capital but also access to specialized labs, equipment, office space, and an extensive network of experts and collaborators to help founders build transformative companies from the ground up.
Serves as the central operational base for The Engine, housing its investment team, administrative staff, and providing state-of-the-art laboratory, fabrication, and office facilities for its portfolio companies.
Over 200,000 square feet of space featuring advanced wet labs, dry labs, machine shops, co-working areas, and event spaces specifically designed to support deep technology development and collaboration.
A mission-driven, collaborative, and intellectually stimulating environment. The culture fosters resilience, innovation, and a hands-on approach to building impactful companies, encouraging interaction between founders, investors, and technical experts.
Its prime Cambridge location offers unparalleled access to talent from MIT and other leading universities, a dense network of researchers, industry partners, and a vibrant startup ecosystem crucial for Tough Tech success.
While The Engine's physical infrastructure and primary operations are based in Cambridge, MA, its investment scope, portfolio companies, and network of collaborators have a global reach. The firm invests in Tough Tech companies addressing worldwide challenges, and its network supports founders with international ambitions in sectors like climate, health, and advanced manufacturing.
750 Main Street
Cambridge
MA
USA
Address: One Broadway, Cambridge, MA 02142
Complements the primary 750 Main Street facility by offering more conventional office environments and meeting spaces, supporting the administrative and networking functions of The Engine and its affiliated startups within the dynamic Cambridge/Boston tech hub.
Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.
As of April 2025, The Engine' leadership includes:
The Engine has been backed by several prominent investors over the years, including:
The Engine's senior executive leadership team has maintained stability over the past 12 months, focusing on the deployment of its funds and support of its portfolio. The firm continues to strategically grow its broader team with specialized talent in investment and platform roles. No major publicly announced departures or new appointments at the General Partner level have occurred in the last 12 months.
Discover the tools The Engine uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
The Engine likely uses common professional email formats. Based on typical venture capital and tech company conventions, emails often use the first name or a combination of first and last names.
firstname@engine.xyz
Format
example@engine.xyz (e.g., katie@engine.xyz)
Example
90%
Success rate
PR Newswire • May 7, 2024
The Engine, the venture capital firm built by MIT, announced the closing of its significantly oversubscribed third fund, Engine Ventures Fund III, at $398 million. This new fund will enable The Engine to continue its mission of investing in early-stage Tough Tech companies poised to address critical global challenges in areas like climate tech, human health, and advanced systems....more
PR Newswire (via Biobot Analytics) • March 26, 2024
Biobot Analytics, a pioneer in wastewater epidemiology and a portfolio company of The Engine, has secured a new contract from the U.S. Centers for Disease Control and Prevention (CDC) to expand its wastewater monitoring services for poliovirus. This contract underscores the critical role of Tough Tech solutions in public health....more
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