What Does Tango Therapeutics Do?

Total employees175
HeadquartersBoston
Founded2017

Tango Therapeutics is a clinical-stage biotechnology company dedicated to discovering and developing a new generation of precision oncology medicines. Leveraging the genetic principle of synthetic lethality, Tango aims to create therapies that target specific cancer vulnerabilities, offering novel treatment options for patients. Their primary focus is on identifying and drugging novel targets to deliver transformative therapies for cancers with high unmet medical need. Key programs include TNG908 (PRMT5 inhibitor for MTAP-deleted tumors) and TNG462 (next-generation PRMT5 inhibitor), alongside a pipeline of discovery-stage assets.

Where Is Tango Therapeutics's Headquarters?

Tango Therapeutics officeTango Therapeutics officeTango Therapeutics officeTango Therapeutics office
*Images sourced via web search. Rights belong to original owners

HQ Function

The Boston headquarters serves as the central nexus for Tango Therapeutics' research and development, clinical operations, corporate strategy, and administrative functions.

Notable Features:

Situated in a modern life sciences building, the facility is equipped with state-of-the-art laboratories for drug discovery and translational research, alongside collaborative office spaces designed to foster scientific innovation.

Work Culture:

Tango Therapeutics fosters a science-driven, innovative, and collaborative work environment. The culture emphasizes urgency and a commitment to addressing unmet needs in oncology, with teams dedicated to rigorous scientific inquiry and translational medicine.

HQ Significance:

Its location in the Boston/Cambridge biotech ecosystem provides Tango with access to world-class scientific talent, leading academic research institutions, and a vibrant network of collaborators and service providers, crucial for advancing its drug development programs.

Values Reflected in HQ: The headquarters' design and functionality likely reflect Tango's core values of scientific excellence, innovation, patient-focus, and collaboration in the pursuit of novel cancer therapies.

Location:

While headquartered in the United States, Tango Therapeutics's operations, particularly clinical trials for its drug candidates, have a global reach. The company collaborates with clinical trial sites and investigators internationally to evaluate the safety and efficacy of its novel oncology treatments in diverse patient populations.

Street Address:

201 Brookline Avenue, Suite 601

City:

Boston

State/Province:

MA

Country:

USA

Where Else Does Tango Therapeutics Operate Around the World?

No additional office locations available.

Buying Intent Signals for Tango Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Tango Therapeutics? Meet the Executive Team

As of April 2025, Tango Therapeutics' leadership includes:

Barbara Weber, M.D. - President and Chief Executive Officer
Daniella Beckman, M.S. - Chief Financial Officer
Adam Crystal, M.D., Ph.D. - President of Research and Development
Alan Huang, Ph.D. - Chief Scientific Officer
Marc Rudoltz, M.D. - Chief Medical Officer
Douglas M. Durant - Chief Business Officer
Jesk Egede, J.D. - General Counsel and Corporate Secretary

Who's Investing in Tango Therapeutics?

Tango Therapeutics has been backed by several prominent investors over the years, including:

Third Rock Ventures
Fidelity Management & Research Company
Boxer Capital, LLC
Access Biotechnology
RA Capital Management
BlackRock Inc.
The Vanguard Group
Casdin Capital, LLC

What Leadership Changes Has Tango Therapeutics Seen Recently?

Hire1
Exits0

In the last 12 months (approx. June 2023 - June 2024), Tango Therapeutics strengthened its executive leadership with the appointment of a new General Counsel. There were no publicly announced departures of named executive officers during this period, although a company-wide restructuring impacting overall headcount occurred in May 2024.

New Appointments:

Jesk Egede, J.D., Jesk Egede appointed as General Counsel and Corporate Secretary.

What Technology (Tech Stack) Is Used byTango Therapeutics?

Discover the tools Tango Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Tango Therapeutics Email Formats and Examples

Tango Therapeutics likely uses a standard corporate email format. Based on common patterns in the biopharmaceutical industry and available information, the most probable format is the first initial followed by the last name.

[first_initial][last]@tangotx.com

Format

jdoe@tangotx.com

Example

75%

Success rate

What's the Latest News About Tango Therapeutics?

GlobeNewswire • June 3, 2024

Tango Therapeutics Reports Updated Data from Phase 1/2 Study of TNG908 in MTAP-Deleted Solid Tumors at ASCO 2024

Tango Therapeutics presented positive updated data from its Phase 1/2 trial of TNG908, an MTA-cooperative PRMT5 inhibitor, demonstrating encouraging anti-tumor activity and a manageable safety profile in patients with MTAP-deleted solid tumors....more

GlobeNewswire • May 7, 2024

Tango Therapeutics Announces Corporate Restructuring to Prioritize Core Programs and Extend Cash Runway

Tango Therapeutics announced a corporate restructuring, including an approximately 20% reduction in its workforce, to focus resources on its lead clinical programs (TNG908, TNG462) and its discovery-stage PRMT5 inhibitor program (TNG260), aiming to extend its cash runway into 2027....more

GlobeNewswire • May 7, 2024

Tango Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Update

Tango Therapeutics reported its Q1 2024 financial results, highlighting progress in its clinical pipeline and outlining strategic priorities following its corporate restructuring. The company reiterated its focus on advancing its key oncology programs....more

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