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SyTrue, acquired by Medline in July 2022, is a healthcare technology company renowned for its advanced Clinical Natural Language Processing (NLP) Operating System, SyHealth. This platform empowers healthcare organizations to transform unstructured clinical data from various sources into clean, structured, and actionable information. By accurately interpreting complex medical narratives, SyTrue's solutions enable improved patient outcomes, operational efficiencies, and data-driven decision-making for providers, payers, and health IT vendors. Its technology is designed to tackle challenges like clinical documentation improvement (CDI), quality reporting, risk adjustment, and clinical research, now enhancing Medline's comprehensive healthcare offerings.
Serves as the primary center for SyTrue's NLP technology development, research, and operations, contributing to Medline's broader healthcare solutions portfolio.
Operates within a modern tech environment, likely leveraging Medline's infrastructure, conducive to software development, AI research, and data analysis. Specific architectural details for a distinct SyTrue-branded building are not emphasized post-acquisition.
Fosters innovation, collaboration, and a focus on solving complex healthcare data challenges, blending SyTrue's agile tech startup spirit with Medline's established corporate environment and mission-driven approach to healthcare.
The Rocklin location represents the core of SyTrue's specialized NLP expertise, contributing significantly to Medline's data intelligence capabilities and its ability to deliver advanced data-driven solutions across the healthcare continuum.
As an integral part of Medline, SyTrue's advanced NLP technology and data solutions contribute to Medline's extensive global operations. While SyTrue's direct operational hubs were primarily US-based, its capabilities now enhance Medline's offerings to international healthcare clients and partners in areas such as data analytics, clinical documentation improvement, and healthcare informatics. Medline has a commercial presence in over 125 countries and territories.
1000 Sylvan Circle
Rocklin
CA
USA
Address: 375 E Lindo Ave, Chico, CA 95926 (Former Key Location)
Supported SyTrue's initial growth, talent acquisition, and development within Northern California's emerging tech ecosystem.
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As of April 2025, SyTrue' leadership includes:
SyTrue has been backed by several prominent investors over the years, including:
Following its acquisition by Medline in July 2022, executive leadership and roles for the SyTrue unit are largely integrated within Medline's broader organizational structure. Specific new hires or exits solely for the 'SyTrue' branded unit in the last 12 months have not been widely publicized. Key original leadership, such as Founder Kyle Silvestro, has continued with SyTrue as part of Medline.
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While SyTrue is now part of Medline, emails originating from team members associated with SyTrue's specific products or legacy operations might use formats linked to the sytrue.com domain. However, it's increasingly common for communication to use Medline's corporate email system. Common professional email formats include first initial followed by last name, or first name.last name.
Commonly `[first_initial][last]@sytrue.com` (e.g., jdoe@sytrue.com) or `[first].[last]@sytrue.com`. Integrated team members likely use Medline's format (e.g., `[first_initial][last]@medline.com`).
Format
ksilvestro@sytrue.com (example, based on potential format for Kyle Silvestro)
Example
70%
Success rate
Medline Newsroom • July 12, 2022
Medline announced its acquisition of SyTrue, a Rocklin, Calif.-based healthcare technology company. SyTrue specializes in AI and natural language processing (NLP) to extract vital clinical data and insights from electronic health records, aiming to enhance Medline's data-driven solutions for the healthcare industry....more
SyTrue Website (Blog/Resource) • October 26, 2023
SyTrue published an article detailing how AI, specifically Natural Language Processing (NLP), can optimize risk adjustment processes for healthcare payers and providers. The piece highlights NLP's ability to accurately extract relevant data from unstructured clinical notes, improving coding accuracy and financial performance....more
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