What Does Sierra Oncology Do?

Total employees95
HeadquartersSan Mateo
Founded2003

Sierra Oncology was a commercial-stage biopharmaceutical company dedicated to delivering targeted therapies for rare cancers. Their lead candidate, momelotinib, a potent, selective, and orally-bioavailable JAK1, JAK2, and ACVR1 inhibitor, showed promising results for myelofibrosis patients with anemia. The company's mission was to address unmet medical needs in hematology and oncology. In July 2022, Sierra Oncology was acquired by GSK, with momelotinib (now marketed as Ojjaara® in the US and Omjjara® in the EU) becoming a key part of GSK's specialty medicines portfolio.

Where Is Sierra Oncology's Headquarters?

Sierra Oncology officeSierra Oncology officeSierra Oncology officeSierra Oncology office
*Images sourced via web search. Rights belong to original owners

HQ Function

Served as the primary hub for corporate operations, research and development strategy, clinical trial management, and business development activities before its acquisition by GSK.

Notable Features:

Located in a modern office park in the San Francisco Bay Area, providing access to a rich biotech ecosystem. The facility was typical of leased office spaces for biopharmaceutical companies of its size.

Work Culture:

Reported to have a focused, science-driven, and collaborative work culture, characteristic of late-stage biotech companies. Employees were dedicated to advancing treatments for patients with rare cancers and addressing unmet medical needs.

HQ Significance:

The San Mateo headquarters was central to Sierra Oncology's operations during its critical phase of developing momelotinib, navigating global clinical trials, and preparing for regulatory approval and commercialization, ultimately leading to its acquisition by GSK.

Values Reflected in HQ: The headquarters likely embodied values of innovation, patient-centricity, scientific rigor, and urgency, crucial for a company developing novel cancer therapies for underserved patient populations.

Location:

Prior to its acquisition by GSK, Sierra Oncology's global presence was primarily defined by its extensive clinical trial programs for momelotinib. These trials were conducted across numerous sites in North America (USA and Canada), Europe (various countries), and the Asia-Pacific region (e.g., Australia). The company was actively preparing for global commercialization, engaging with regulatory authorities in key markets worldwide.

Street Address:

1820 Gateway Drive, Suite 110

City:

San Mateo

State/Province:

CA

Country:

USA

Where Else Does Sierra Oncology Operate Around the World?

Vancouver, British Columbia, Canada

Address: Historically, a registered address was maintained, e.g., 720 Robson Street, Suite 510, Vancouver, BC, V6Z 1A1 (for Sierra Oncology Canada Inc.)

Facilitated Canadian corporate registration and compliance. Provided a point of contact within the Canadian life sciences sector and supported any Canada-specific research or clinical operations.

Buying Intent Signals for Sierra Oncology

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Sierra Oncology? Meet the Executive Team

As of April 2025, Sierra Oncology' leadership includes:

Stephen G. Dilly, MBBS, PhD - President and Chief Executive Officer
William D. Turner - Chief Financial Officer
Barbara Klencke, MD - Chief Medical Officer
Kevin G. Surveyer, CPA, CA - Chief Business Officer
Sukhi Jagpal, RPh - Chief Operating Officer

Who's Investing in Sierra Oncology?

Sierra Oncology has been backed by several prominent investors over the years, including:

Longitude Capital
OrbiMed Advisors
Frazier Healthcare Partners
Vivo Capital
BlackRock Inc.
The Vanguard Group
RA Capital Management

What Leadership Changes Has Sierra Oncology Seen Recently?

Hire1
Exits5

The most significant executive event for Sierra Oncology was its acquisition by GSK in July 2022, leading to the transition of its leadership team as the company was integrated. A key hire before the acquisition was Sukhi Jagpal as COO in early 2022.

Departures

Stephen G. Dilly, MBBS, PhD, Departed CEO role following the completion of GSK's acquisition of Sierra Oncology.
William D. Turner, Departed CFO role following the completion of GSK's acquisition of Sierra Oncology.
Barbara Klencke, MD, Departed CMO role following the completion of GSK's acquisition of Sierra Oncology.
Kevin G. Surveyer, CPA, CA, Departed CBO role following the completion of GSK's acquisition of Sierra Oncology.
Sukhi Jagpal, RPh, Departed COO role following the completion of GSK's acquisition of Sierra Oncology; had joined in Feb 2022.

New Appointments:

Sukhi Jagpal, RPh, Appointed as Chief Operating Officer to strengthen operational capabilities as Sierra advanced momelotinib towards potential commercialization prior to the GSK acquisition.

What Technology (Tech Stack) Is Used bySierra Oncology?

Discover the tools Sierra Oncology uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Sierra Oncology Email Formats and Examples

Prior to its acquisition by GSK in July 2022, Sierra Oncology likely used common corporate email formats. A frequently observed pattern for companies of this nature is [first_initial][last]@domain.com. The @sierraoncology.com domain is no longer actively used for widespread new employee communication post-acquisition.

[first_initial][last]@sierraoncology.com

Format

jdoe@sierraoncology.com

Example

75%

Success rate

What's the Latest News About Sierra Oncology?

GSK plc • January 26, 2024

GSK's Omjjara (momelotinib) Authorised in the European Union for Myelofibrosis Patients with Anaemia

The European Commission granted marketing authorisation for Omjjara (momelotinib) for treating disease-related splenomegaly or symptoms in adult myelofibrosis patients with moderate to severe anaemia. This drug was originally developed by Sierra Oncology....more

GSK plc • September 15, 2023

GSK's Ojjaara (momelotinib) Approved in the US as the First and Only Treatment for Myelofibrosis Patients with Anemia

The US Food and Drug Administration (FDA) approved Ojjaara (momelotinib) for the treatment of myelofibrosis in adult patients with anemia. This marks a significant milestone for the drug developed by Sierra Oncology and acquired by GSK....more

GSK plc • July 1, 2022

GSK Completes Acquisition of Sierra Oncology

GSK plc announced it had completed its acquisition of Sierra Oncology, Inc., for $55 per share of common stock in cash, representing an approximate total equity value of $1.9 billion. Sierra Oncology was focused on targeted therapies for rare cancers....more

Sierra Oncology / GSK plc • April 13, 2022

GSK to Acquire Sierra Oncology for $1.9 Billion

GSK plc and Sierra Oncology, Inc. announced they entered into a definitive agreement under which GSK will acquire Sierra Oncology, a California-based, late-stage biopharmaceutical company focused on targeted therapies for rare cancers, for $1.9 billion....more

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