What Does Sage Therapeutics Do?

Total employees500
HeadquartersCambridge
Founded2010

Sage Therapeutics is a late-stage biopharmaceutical company dedicated to discovering, developing, and delivering life-changing medicines for people with brain health disorders. Their R&D efforts focus on modulating two critical central nervous system receptor systems, GABA and NMDA. Sage aims to address unmet medical needs in areas such as depression, neurology, and neuropsychiatry by leveraging its expertise in brain circuitry and neurosteroids. Their first commercial product, ZURZUVAE™ (zuranolone), co-developed and co-commercialized with Biogen, is approved for postpartum depression in the U.S.

Where Is Sage Therapeutics's Headquarters?

HQ Function

The Cambridge headquarters serves as the central hub for Sage's executive leadership, research and development operations, clinical development, commercial strategy, and corporate administrative functions. It is the primary site for strategic decision-making and scientific innovation.

Notable Features:

The headquarters is situated in a modern life sciences facility in Kendall Square, offering state-of-the-art laboratory and office spaces. Its location provides close proximity to leading academic institutions like MIT and Harvard, numerous other biotech companies, and venture capital firms, fostering collaboration and innovation.

Work Culture:

Sage Therapeutics promotes a work culture centered on patients, driven by science, and built on collaboration. They emphasize values such as courage, passion, and urgency, aiming to create an inclusive environment where employees are empowered to make a difference in brain health.

HQ Significance:

The Cambridge headquarters' location in Kendall Square is highly significant, placing Sage at the epicenter of biopharmaceutical research and development. This provides unparalleled access to top talent, cutting-edge research, potential partnerships, and a vibrant scientific community, crucial for a company focused on neuroscience innovation.

Values Reflected in HQ: The headquarters' state-of-the-art facilities and prime location reflect Sage's commitment to scientific excellence, innovation, and collaboration. It's designed to foster the discovery and development of novel therapies for complex brain disorders.

Location:

While Sage Therapeutics' primary operational base, including its headquarters for research, development, and corporate functions, is in Cambridge, Massachusetts, USA, its impact and activities extend globally. The company conducts multinational clinical trials to support drug development and regulatory submissions in various countries. For its commercialized products, like ZURZUVAE™, it collaborates with partners (e.g., Biogen) that have established global commercial capabilities. Sage's engagement with the international scientific and medical community is also a key aspect of its global reach.

Street Address:

215 First Street

City:

Cambridge

State/Province:

Massachusetts

Country:

USA

Where Else Does Sage Therapeutics Operate Around the World?

No additional office locations available.

Buying Intent Signals for Sage Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Sage Therapeutics? Meet the Executive Team

As of April 2025, Sage Therapeutics' leadership includes:

Barry Greene - Chief Executive Officer
Kimi Iguchi - Chief Financial Officer
Laura Gault, M.D., Ph.D. - Chief Medical Officer
Jim Doherty, Ph.D. - Chief Development Officer
Chris Benecchi - Chief Business Officer
Mark H.N. Quigley - Chief Legal Officer and Corporate Secretary
Megan Miller - Chief People & Experience Officer

Who's Investing in Sage Therapeutics?

Sage Therapeutics has been backed by several prominent investors over the years, including:

The Vanguard Group, Inc.
BlackRock, Inc.
Price T. Rowe Associates, Inc.
State Street Corporation
RA Capital Management
Artisan Partners Limited Partnership

What Leadership Changes Has Sage Therapeutics Seen Recently?

Hire1
Exits3

Over the past 12 months (approx. May 2023 - May 2024), Sage Therapeutics has undergone notable executive transitions, including a key retirement in R&D leadership, the appointment of a new Chief Development Officer, and departures of other senior executives as part of strategic realignments and company evolution.

Departures

Geno Germano, Geno Germano departed from his role as Chief Patient and Commercial Officer.
Al Robichaud, Ph.D., Al Robichaud retired as Chief Scientific Officer at the end of 2023.
Mike Cloonan, Mike Cloonan stepped down as Chief Operating Officer as part of a company reorganization.

New Appointments:

Jim Doherty, Ph.D., Jim Doherty, Ph.D., was appointed as Chief Development Officer, succeeding Al Robichaud and taking leadership of the company's R&D organization.

What Technology (Tech Stack) Is Used bySage Therapeutics?

Discover the tools Sage Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Sage Therapeutics Email Formats and Examples

Sage Therapeutics commonly utilizes the email format [first].[last]@sagerx.com. For instance, an employee named Jane Doe would likely have the email address jane.doe@sagerx.com. While this is a frequently observed pattern, other formats might be used in specific cases or for different departments.

[first].[last]@sagerx.com

Format

jane.doe@sagerx.com

Example

75%

Success rate

What's the Latest News About Sage Therapeutics?

Sage Therapeutics Investor RelationsMay 7, 2024

Sage Therapeutics Reports First Quarter 2024 Financial Results and Highlights Pipeline Progress

Sage Therapeutics announced its financial results for the first quarter of 2024, providing updates on the U.S. commercial launch of ZURZUVAE™ (zuranolone) for postpartum depression, progress in its pipeline programs including dalzanemdor (SAGE-718) and SAGE-324, and reiterated financial guidance....more

Sage Therapeutics Press ReleaseJanuary 4, 2024

Sage Therapeutics Announces Pipeline Goals and Strategic Reorganization to Drive Efficiency and Support Future Growth

Sage Therapeutics outlined its key pipeline objectives for 2024 and announced a strategic reorganization, including a workforce reduction, aimed at enhancing operational efficiency and focusing resources on priority programs to drive future growth and value....more

Sage Therapeutics Press ReleaseAugust 4, 2023

Sage Therapeutics and Biogen Announce FDA Approval of ZURZUVAE™ (zuranolone) for the Treatment of Adults with Postpartum Depression (PPD) and FDA Complete Response Letter for Major Depressive Disorder (MDD)

Sage Therapeutics and its partner Biogen received FDA approval for ZURZUVAE™ (zuranolone) as the first oral medication specifically for adults with postpartum depression. Concurrently, the FDA issued a Complete Response Letter for the New Drug Application for zuranolone in major depressive disorder, indicating that additional studies are needed for that indication....more

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