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Prelude Therapeutics's Overview

Total employees84
HeadquartersWilmington
Founded2016

Prelude Therapeutics is a clinical-stage biopharmaceutical company dedicated to the discovery and development of novel, small molecule therapies for patients with underserved cancers. The company focuses on designing and advancing potential first-in-class and best-in-class medicines that target critical cancer cell pathways. Prelude's pipeline includes several candidates being evaluated in clinical trials, aiming to address significant unmet medical needs in oncology with precision therapeutics.

Where is Prelude Therapeutics's Headquarters?

HQ Function

The headquarters serves as the primary center for Prelude Therapeutics' research and development activities, clinical operations, corporate administration, and strategic leadership.

Notable Features:

The facility is part of a redeveloped life sciences campus, featuring modern laboratory spaces and offices designed to support cutting-edge biopharmaceutical research and drug development.

Work Culture:

Prelude fosters a dynamic, science-driven work culture focused on innovation, collaboration, and a strong commitment to patients. The environment encourages rigorous scientific inquiry and a sense of urgency in developing new cancer treatments.

HQ Significance:

Located in the Delaware biotechnology hub, the headquarters benefits from access to a skilled talent pool, proximity to research institutions, and a supportive ecosystem for life sciences companies. This strategic location aids its research and collaboration efforts.

Values Reflected in HQ: The headquarters' focus on advanced research facilities and a collaborative environment reflects Prelude's core values of scientific excellence, innovation, integrity, and a patient-centric approach to drug discovery.

Location:

While Prelude Therapeutics is headquartered in the United States, its clinical development programs often involve trial sites across multiple countries, indicating a global research footprint. The company's strategic vision includes seeking regulatory approvals and making its therapies available to patients worldwide, if successfully developed and approved. Although direct physical office locations are primarily U.S.-based, functions such as clinical operations, regulatory affairs, and potential partnerships support a global outlook.

Street Address:

200 Powder Mill Road

City:

Wilmington

State/Province:

Delaware

Country:

USA

Prelude Therapeutics's Global Presence

Buying Intent Signals for Prelude Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Executive Team of Prelude Therapeutics

As of April 2025, Prelude Therapeutics' leadership includes:

Kris Vaddi, Ph.D. - Founder, Chief Executive Officer
Jane Huang, M.D. - President and Chief Medical Officer
Laurent Chardonnet, M.B.A. - Chief Financial Officer
Peggy Scherle, Ph.D. - Chief Scientific Officer
Chris Waddick - Chief Operating Officer
Andrew D.C. Levi, J.D. - Chief Legal Officer and Corporate Secretary

Investors of Prelude Therapeutics

Prelude Therapeutics has been backed by several prominent investors over the years, including:

OrbiMed Advisors LLC
Baker Bros. Advisors LP
Fidelity Management & Research Company LLC (FMR LLC)
RA Capital Management, L.P.
Redmile Group, LLC
Deep Track Capital, LP
Logos Capital

Executive New Hires/Exits in the Last 12 Months

Hire2
Exits2

Over the past 12 months, Prelude Therapeutics has made key changes to its executive team, including appointing a new Chief Financial Officer and a new Chief Operating Officer, alongside the departures of their predecessors, to support its ongoing clinical development and strategic objectives.

Departures

Michele Porreca, Michele Porreca departed as Chief Financial Officer.
Marty S. VanTrieste, Marty S. VanTrieste resigned as Chief Operating Officer.

New Appointments:

Laurent Chardonnet, Laurent Chardonnet appointed as new Chief Financial Officer.
Chris Waddick, Chris Waddick appointed as new Chief Operating Officer.

Technology (Tech Stack) used by Prelude Therapeutics

Discover the tools Prelude Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Prelude Therapeutics Email Formats and Examples

Prelude Therapeutics primarily uses the email format of [first_initial][last_name]@preludetx.com. This is a common structure for corporate communications within the company.

[first_initial][last]@preludetx.com

Format

kvaddi@preludetx.com

Example

90%

Success rate

News and media

GlobeNewswireMay 9, 2024

Prelude Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Update

Prelude Therapeutics announced its financial results for Q1 2024, highlighting progress in its clinical pipeline, including updates on PRT2527, PRT3645, and PRT3789. The company confirmed its cash runway extends into the fourth quarter of 2025....more

GlobeNewswireMarch 4, 2024

Prelude Therapeutics Appoints Chris Waddick as Chief Operating Officer

Prelude Therapeutics announced the appointment of Chris Waddick as its new Chief Operating Officer. Mr. Waddick brings over 20 years of experience in the biopharmaceutical industry, with a strong background in operations, commercial strategy, and corporate development....more

GlobeNewswireFebruary 28, 2024

Prelude Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update

Prelude Therapeutics reported its financial results for the fourth quarter and full year ended December 31, 2023. The company provided updates on its clinical programs and outlined its strategic priorities for advancing its pipeline of potential cancer therapies....more

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