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Osage Partners is a venture capital firm comprised of two distinct investment practices: Osage Venture Partners (OVP) and Osage University Partners (OUP). OVP, founded in 2005, focuses on investing in early-stage, post-revenue B2B software companies primarily located on the East Coast of the United States. OUP specializes in partnering with premier research universities and institutions to invest in deep science and technology companies at their earliest stages, often as university spinouts. Together, Osage Partners aims to identify and support innovative entrepreneurs and transformative technologies from inception through growth.
Serves as the primary operational hub for investment decision-making, portfolio company support, fund management, and administrative functions for both OVP and OUP.
Located in a modern office building in a suburban setting with good accessibility to Philadelphia and major transportation routes. The facilities are designed to support a collaborative and analytical work environment.
The work culture at Osage Partners is characterized by intellectual curiosity, rigorous analysis, collaborative teamwork, and a strong commitment to partnering with entrepreneurs and academic institutions. There's a focus on long-term value creation and fostering innovation.
The Bala Cynwyd headquarters is strategically positioned near Philadelphia's growing technology and life sciences ecosystem, as well as numerous research universities, facilitating deal sourcing, networking, and talent acquisition.
Osage Partners primarily focuses its investment activities within the United States. Osage Venture Partners (OVP) concentrates on the East Coast. Osage University Partners (OUP), while investing predominantly in US-based university spinouts, also maintains a European presence and global network to identify and support investment opportunities emerging from leading international research institutions. This involves building relationships with universities, research labs, and entrepreneurs worldwide to access cutting-edge technologies.
One Presidential Boulevard, Suite 310
Bala Cynwyd
Pennsylvania
USA
Address: Salesforce Tower, 950 East Paces Ferry Rd NE, Suite 825, Atlanta, GA 30326
Strengthens OVP's presence in the dynamic Southeast tech market, allowing for closer engagement with entrepreneurs, startups, and industry networks in the region.
Address: 951 Mariners Island Blvd, Suite 300, San Mateo, CA 94404
Provides OUP with a strategic presence in Silicon Valley, enabling close collaboration with leading universities, research labs, and the vibrant West Coast venture ecosystem.
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As of April 2025, Osage Venture Partners' leadership includes:
Osage Venture Partners has been backed by several prominent investors over the years, including:
Over the past 12 months (approaching June 2023 - May 2024), Osage Partners, particularly its Osage University Partners (OUP) arm, has strengthened its leadership with a key Partner appointment. No prominent executive departures have been publicly announced during this period.
Discover the tools Osage Venture Partners uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
Osage Partners commonly uses an email format consisting of the employee's first initial followed by their last name, at their domain osagepartners.com. For example, an employee named Jane Doe would likely have the email address jdoe@osagepartners.com.
[first_initial][last]@osagepartners.com
Format
rsmith@osagepartners.com
Example
90%
Success rate
PR Newswire • May 9, 2024
Osage University Partners (OUP), part of Osage Partners, announced the final closing of its fourth core fund, OUP Core Fund IV, L.P., at $325 million, exceeding its target. The fund will continue OUP's strategy of investing in deep science and technology companies commercializing groundbreaking university research....more
Business Wire • April 30, 2024
Vivodyne, a biotech company and an existing portfolio company of Osage Venture Partners (an arm of Osage Partners), announced it has raised $38 million in Series A funding. This capital will be used to scale its AI-powered platform for testing new drug candidates on lab-grown, lifelike human organoids....more
FinSMEs / OVP Insights • November 2, 2023
Osage Venture Partners (OVP), part of Osage Partners, participated in the $5 million seed funding round for Pacesetter, a B2B SaaS platform designed to enhance enterprise sales execution. This investment underscores OVP's commitment to supporting innovative early-stage B2B software companies on the East Coast....more
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