What Does Maze Therapeutics Do?

Total employees138
HeadquartersSouth San Francisco
Founded2018

Maze Therapeutics is a clinical-stage biotechnology company dedicated to developing a new generation of precision medicines for patients with genetically defined diseases. By leveraging human genetics, functional genomics, and advanced data science, Maze aims to identify and validate novel therapeutic targets and create transformative therapies. Their focus is on translating complex genetic insights into impactful treatments, addressing significant unmet medical needs in areas like Pompe disease, chronic kidney disease, and other rare conditions.

Where Is Maze Therapeutics's Headquarters?

HQ Function

The headquarters serves as the central hub for Maze Therapeutics' research and development, clinical operations, corporate strategy, and administrative functions.

Notable Features:

Located in a prominent biotechnology hub, the facility likely features state-of-the-art laboratory spaces, modern office environments, and collaborative workspaces designed to foster innovation.

Work Culture:

Maze Therapeutics fosters a work culture centered on scientific rigor, collaboration, patient-centricity, and innovation. Employees (Mazers) are encouraged to be bold, pursue cutting-edge science, and work together to solve complex biological problems.

HQ Significance:

The South San Francisco headquarters is strategically significant due to its proximity to a rich ecosystem of academic institutions, research organizations, and other biotech companies, facilitating collaborations and talent acquisition.

Values Reflected in HQ: The headquarters' design and operations likely reflect Maze's core values of pioneering science, commitment to patients, integrity, and fostering a dynamic, inclusive environment for its team.

Location:

While headquartered in South San Francisco, Maze Therapeutics conducts clinical trials and engages in research collaborations that may span multiple countries. Their commitment to addressing genetically defined diseases necessitates a global outlook in terms of patient populations, research partnerships, and potential future market access.

Street Address:

171 Oyster Point Blvd, Suite 300

City:

South San Francisco

State/Province:

CA

Country:

USA

Where Else Does Maze Therapeutics Operate Around the World?

No additional office locations available.

Buying Intent Signals for Maze Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Maze Therapeutics? Meet the Executive Team

As of April 2025, Maze Therapeutics' leadership includes:

Jason Coloma, Ph.D. - Chief Executive Officer
Harold S. Bernstein, M.D., Ph.D. - President, Head of Research and Development
Sarah Noonberg, M.D., Ph.D. - Chief Medical Officer
Naveen Krishnan, M.D., M.Phil. - Chief Financial Officer
Matthew R. Nussbaum, J.D., Ph.D. - Chief Business Officer
Ali Identifying, Ph.D. - Chief Scientific Officer
Tim Hoctor - Chief People Officer
Jessica Stitt, J.D. - General Counsel

Who's Investing in Maze Therapeutics?

Maze Therapeutics has been backed by several prominent investors over the years, including:

Third Rock Ventures
ARCH Venture Partners
GV (Google Ventures)
Foresite Capital
Casdin Capital
Matrix Capital Management
General Catalyst
Andreessen Horowitz (a16z Bio + Health)
Woodline Partners LP
Longitude Capital
OrbiMed
Nextech Invest
Section 32

What Leadership Changes Has Maze Therapeutics Seen Recently?

Hire2
Exits0

Over the past 12 months, Maze Therapeutics has strengthened its executive team with key appointments in finance and human resources, reflecting its continued growth and strategic development. No major executive departures have been publicly announced during this period.

New Appointments:

Naveen Krishnan, M.D., M.Phil., Naveen Krishnan appointed as new Chief Financial Officer, bringing extensive experience in biotech finance.
Tim Hoctor, Tim Hoctor appointed as new Chief People Officer to foster company culture and manage human capital.

What Technology (Tech Stack) Is Used byMaze Therapeutics?

Discover the tools Maze Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Maze Therapeutics Email Formats and Examples

Maze Therapeutics likely uses a common corporate email format. Based on industry standards and available information, the primary format is often a combination of the employee's first initial and last name.

[first_initial][last]@mazetx.com

Format

jcoloma@mazetx.com

Example

85%

Success rate

What's the Latest News About Maze Therapeutics?

Business WireMay 7, 2024

Maze Therapeutics Presents Data at the ASGCT 27th Annual Meeting Highlighting the Potential of its MZE001 Program to Treat Pompe Disease

Maze Therapeutics shared preclinical data on MZE001, an oral glycogen synthase (GYS1) inhibitor, for Pompe disease. The data demonstrated significant reductions in glycogen storage in multiple preclinical models, supporting its potential as a substrate reduction therapy....more

GlobeNewswireApril 8, 2024

Maze Therapeutics to Present Data at the American Academy of Neurology (AAN) 2024 Annual Meeting Highlighting a Novel Approach to Treating Chronic Kidney Disease

Maze Therapeutics announced it would present preclinical data on its APOL1 inhibitor program for APOL1-mediated kidney disease (AMKD) at the AAN 2024 Annual Meeting, showcasing a potential new treatment avenue....more

GlobeNewswireFebruary 28, 2024

Maze Therapeutics Announces First Patient Dosed in Phase 1 Clinical Trial of MZE829 for the Treatment of Maternally Inherited Leigh Syndrome and MELAS

Maze Therapeutics initiated a Phase 1 clinical trial for MZE829, an oral mtDNA polymerase gamma (POLG) inhibitor, aimed at treating Maternally Inherited Leigh Syndrome and MELAS, two rare mitochondrial diseases with no approved therapies....more

Maze Therapeutics Press ReleaseSeptember 6, 2023

Maze Therapeutics Appoints Naveen Krishnan, M.D., M.Phil., as Chief Financial Officer

Maze Therapeutics announced the appointment of Naveen Krishnan, M.D., M.Phil., as its new Chief Financial Officer. Dr. Krishnan brings extensive experience in healthcare finance and investment to the role....more

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