What Does Madrigal Pharmaceuticals Do?

Total employees631
HeadquartersWest Conshohocken
Founded2016

Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL) is a clinical-stage biopharmaceutical company dedicated to the development and commercialization of innovative therapies for cardiovascular, metabolic, and liver diseases. Their primary focus has been on non-alcoholic steatohepatitis (NASH), a severe form of non-alcoholic fatty liver disease. Madrigal's lead product candidate, Rezdiffra™ (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor (THR)-β selective agonist. In March 2024, Rezdiffra received FDA approval for the treatment of adult patients with noncirrhotic NASH with moderate to advanced liver fibrosis, making it the first and only medication approved for this indication. The company is committed to addressing significant unmet medical needs and improving patient outcomes through pioneering science.

Where Is Madrigal Pharmaceuticals's Headquarters?

HQ Function

Serves as the central hub for all corporate, strategic, research and development oversight, and commercial operations.

Notable Features:

Modern office facilities located within a suburban business park, designed to support administrative functions, clinical development oversight, and commercialization planning.

Work Culture:

The headquarters fosters a dynamic, science-driven, and collaborative work environment. There is a strong emphasis on innovation, patient-centricity, and achieving milestones, particularly as the company transitions into a commercial-stage entity.

HQ Significance:

The headquarters is critical for Madrigal's operations, housing its leadership team and centralizing decision-making for its clinical programs, regulatory strategies, and the commercial launch of Rezdiffra™.

Values Reflected in HQ: The headquarters environment likely reflects Madrigal's core values of scientific excellence, urgency in addressing patient needs, integrity, and collaboration.

Location:

Madrigal Pharmaceuticals' global presence has primarily been characterized by its international clinical trial sites for Rezdiffra™. With FDA approval secured in the U.S., the initial commercial focus is on the American market. The company may pursue regulatory approvals and commercialization in other key international regions in the future, expanding its global operational footprint for medical affairs, market access, and sales.

Street Address:

200 Barr Harbor Drive, Suite 200

City:

West Conshohocken

State/Province:

PA

Country:

United States

Where Else Does Madrigal Pharmaceuticals Operate Around the World?

No additional office locations available.

Buying Intent Signals for Madrigal Pharmaceuticals

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Madrigal Pharmaceuticals? Meet the Executive Team

As of April 2025, Madrigal Pharmaceuticals' leadership includes:

Bill Sibold - Chief Executive Officer
Becky Taub, M.D. - Chief Medical Officer and President of Research & Development
Alex Drapacz - Chief Financial Officer
Clint Wallace - Chief Business Officer
Rob MacKay - Chief Operations Officer
Stephen Webster - Chief Legal and Compliance Officer, Corporate Secretary

Who's Investing in Madrigal Pharmaceuticals?

Madrigal Pharmaceuticals has been backed by several prominent investors over the years, including:

Baker Bros. Advisors LP
The Vanguard Group, Inc.
BlackRock Fund Advisors
Fidelity Management & Research Company LLC (FMR Co LLC)
T. Rowe Price Associates, Inc.

What Leadership Changes Has Madrigal Pharmaceuticals Seen Recently?

Hire3
Exits0

Madrigal Pharmaceuticals has significantly bolstered its executive team in the past 12 months, appointing a new CEO, COO, and CLCO. These changes align with the company's strategic evolution into a commercial-stage organization following the landmark FDA approval of Rezdiffra™. Dr. Paul Friedman transitioned from CEO to Chairman of the Board, ensuring continuity of leadership.

New Appointments:

Bill Sibold, Bill Sibold appointed as new CEO.
Rob MacKay, Rob MacKay appointed as new COO.
Stephen Webster, Stephen Webster appointed as new CLCO.

What Technology (Tech Stack) Is Used byMadrigal Pharmaceuticals?

Discover the tools Madrigal Pharmaceuticals uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Madrigal Pharmaceuticals Email Formats and Examples

Madrigal Pharmaceuticals Inc. likely utilizes common corporate email formats. Based on industry standards and observed patterns for executives, one of the probable primary formats is the first initial followed by the last name.

[first_initial][last]@madrigalpharma.com

Format

jdoe@madrigalpharma.com

Example

75%

Success rate

What's the Latest News About Madrigal Pharmaceuticals?

ir.madrigalpharma.comMarch 14, 2024

Madrigal Pharmaceuticals Inc. Announces FDA Approval of Rezdiffra™ (resmetirom) for the Treatment of Patients with Noncirrhotic Nonalcoholic Steatohepatitis (NASH) with Moderate to Advanced Liver Fibrosis

Madrigal Pharmaceuticals announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval for Rezdiffra™ (resmetirom) for the treatment of adult patients with noncirrhotic nonalcoholic steatohepatitis (NASH) with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis). Rezdiffra is the first and only once-daily, oral medication approved for NASH....more

ir.madrigalpharma.comMay 8, 2024

Madrigal Pharmaceuticals Inc. Reports First Quarter 2024 Financial Results and Provides Corporate Update

Madrigal Pharmaceuticals reported its financial results for the first quarter ended March 31, 2024, and provided an update on the U.S. commercial launch of Rezdiffra™, as well as other corporate developments. The company highlighted its focus on ensuring patient access and physician education for its newly approved NASH treatment....more

ir.madrigalpharma.comJune 5, 2024

Madrigal Pharmaceuticals Inc. Highlights New Rezdiffra™ (resmetirom) Data at EASL Congress 2024, Reinforcing Efficacy and Safety Profile in NASH with Fibrosis

Madrigal announced new data presentations for Rezdiffra™ (resmetirom) at the European Association for the Study of the Liver (EASL) Congress 2024. The presentations included further analyses from the pivotal Phase 3 MAESTRO-NASH trial, reinforcing the drug's efficacy in resolving NASH and improving liver fibrosis, alongside its generally well-tolerated safety profile....more

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