What Does Loxo Oncology Do?

Total employees350
HeadquartersStamford
Founded2013

Loxo Oncology, founded in 2013 and acquired by Eli Lilly and Company in 2019, is a biopharmaceutical group dedicated to discovering, developing, and commercializing highly selective medicines for patients with genomically defined cancers. Known for its rapid development of targeted therapies such as Vitrakvi (larotrectinib), Retevmo (selpercatinib), and Jaypirca (pirtobrutinib), Loxo Oncology now operates as a key research and development engine within Lilly's oncology division. It continues to advance a pipeline of innovative cancer treatments, leveraging precision medicine to address unmet patient needs.

Where Is Loxo Oncology's Headquarters?

HQ Function

Central hub for Loxo at Lilly's oncology drug discovery, translational research, and clinical development programs, specializing in targeted therapies.

Notable Features:

State-of-the-art laboratory facilities and collaborative workspaces designed to accelerate innovative cancer research.

Work Culture:

Retains a biotech-like agility and strong scientific focus within the larger Eli Lilly framework. Emphasizes rapid innovation, patient impact, and collaborative teamwork.

HQ Significance:

Crucial R&D site for Lilly's precision oncology strategy, building on Loxo's legacy of groundbreaking targeted drug development and approvals.

Values Reflected in HQ: Dedication to scientific rigor, innovation in precision medicine, urgency in addressing patient needs, and a collaborative approach to solving complex cancer challenges.

Location:

As a research and development group within Eli Lilly and Company, Loxo Oncology's work is supported by Lilly's extensive global infrastructure. This includes global clinical trial operations across numerous countries, worldwide regulatory affairs, manufacturing capabilities, and commercial reach for its approved medicines. While Loxo at Lilly's primary R&D sites are in the U.S., its impact and the reach of its therapies are global through the Eli Lilly network.

Street Address:

200 Commons, Suite 200

City:

Stamford

State/Province:

CT

Country:

USA

Where Else Does Loxo Oncology Operate Around the World?

South San Francisco, CA, USA

Address: 1700 Owens Street, San Francisco, CA 94158 (Eli Lilly Campus)

To tap into West Coast scientific talent, foster collaborations with academic institutions and biotech companies, and advance specific programs within Loxo at Lilly's oncology pipeline.

Boulder, CO, USA

Address: 3200 Walnut St, Boulder, CO 80301 (Eli Lilly Campus, formerly Array BioPharma)

Leverages specific scientific expertise and infrastructure in the Boulder region, supporting the broader goals of Loxo at Lilly's oncology pipeline development.

New York City, NY, USA

Address: Alexandria Center for Life Science, 450 East 29th Street, New York, NY 10016 (Eli Lilly New York)

To engage with the New York academic and biotech ecosystem, access diverse talent, and support various research and development initiatives.

Buying Intent Signals for Loxo Oncology

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Loxo Oncology? Meet the Executive Team

As of April 2025, Loxo Oncology' leadership includes:

Jake Van Naarden - Executive Vice President and President, Lilly Oncology (formerly CEO, Loxo Oncology at Lilly)
David Hyman, M.D. - Chief Medical Officer, Eli Lilly and Company (formerly Chief Medical Officer, Loxo Oncology at Lilly)
Andrew (Andy) D. Simmons, Ph.D. - Senior Vice President, Loxo at Lilly and Head of Oncology Research, Lilly Research Laboratories
Nisha Nanda, Ph.D. - Chief Development Officer, Loxo at Lilly

Who's Investing in Loxo Oncology?

Loxo Oncology has been backed by several prominent investors over the years, including:

Aisling Capital
OrbiMed Advisors
New Enterprise Associates (NEA)
RA Capital Management
Deerfield Management
Perceptive Advisors
venBio Partners
Fidelity Management & Research Company
Redmile Group
Nextech Invest

What Leadership Changes Has Loxo Oncology Seen Recently?

Hire0
Exits0

Following its acquisition by Eli Lilly and Company in 2019, Loxo Oncology operates as an integrated R&D group. Standalone executive news for 'Loxo Oncology, Inc.' is generally not applicable; changes are part of Eli Lilly's broader organizational announcements. No specific 'Loxo Oncology, Inc.' branded executive hires or exits have been publicly announced in the last 12 months as a distinct entity.

Departures

N/A, Executive changes are managed within Eli Lilly and Company since the 2019 acquisition.

New Appointments:

N/A, Executive changes are managed within Eli Lilly and Company since the 2019 acquisition.

What Technology (Tech Stack) Is Used byLoxo Oncology?

Discover the tools Loxo Oncology uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Loxo Oncology Email Formats and Examples

As Loxo Oncology is part of Eli Lilly and Company, employees typically use Eli Lilly's corporate email format. A common format at Eli Lilly is [last]_[first]@lilly.com. Other formats like [first_initial][last]@lilly.com may also be in use.

[last]_[first]@lilly.com

Format

doe_john@lilly.com

Example

85%

Success rate

What's the Latest News About Loxo Oncology?

Eli Lilly and CompanyJune 3, 2024

Lilly Highlights Jaypirca's Potential at ASCO 2024 with New Data

Eli Lilly and Company presented new data at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, showcasing the broad clinical utility of Jaypirca (pirtobrutinib), a Loxo at Lilly-developed therapy, across various B-cell malignancies....more

Eli Lilly and CompanyDecember 1, 2023

Lilly's Jaypirca (pirtobrutinib) Receives FDA Approval for Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)

The U.S. Food and Drug Administration (FDA) approved Jaypirca™ (pirtobrutinib) for adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) who have received at least two prior lines of therapy, including a BTK inhibitor and a BCL-2 inhibitor. Jaypirca was developed by Loxo at Lilly....more

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