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Leap Therapeutics's Overview

Total employees51
HeadquartersLexington
Founded

Leap Therapeutics (NASDAQ: LPTX) is a clinical-stage biopharmaceutical company focused on acquiring and developing novel, targeted and immuno-oncology therapeutics. Their primary mission is to address significant unmet medical needs in cancer treatment. Leap's leading drug candidate, DKN-01, is a humanized monoclonal antibody targeting the Dickkopf-1 (DKK1) protein, a key modulator in Wnt signaling pathways implicated in cancer. DKN-01 is currently being evaluated in multiple clinical trials for various cancers, particularly gastroesophageal, gynecologic, and prostate cancers, often in combination with other therapies.

Where is Leap Therapeutics's Headquarters?

HQ Function

The Lexington headquarters serves as the central node for Leap Therapeutics's corporate administration, research and development oversight, clinical operations management, and strategic planning.

Notable Features:

The facility is situated in a modern life sciences campus, likely equipped with or providing access to advanced laboratory and office spaces tailored for biopharmaceutical research and development.

Work Culture:

As a clinical-stage biotech, the work culture at Leap Therapeutics likely fosters innovation, scientific rigor, collaboration, and a strong patient-first mentality. Employees are driven by the goal of advancing treatments for difficult-to-treat cancers.

HQ Significance:

The headquarters' location in the Boston-Cambridge biotech cluster provides invaluable access to a rich ecosystem of academic research, potential industry collaborations, skilled workforce, and venture capital, all critical for growth and innovation in the biopharmaceutical sector.

Values Reflected in HQ: The headquarters' focus on enabling research and clinical development reflects Leap Therapeutics's core values of scientific excellence, innovation, and dedication to improving patient outcomes in oncology.

Location:

Leap Therapeutics's global presence is primarily manifested through its clinical trial operations and collaborations. While its core R&D and corporate functions are centralized in the United States, the company engages with international clinical research sites, investigators, and contract research organizations (CROs) to conduct studies for its pipeline candidates like DKN-01. This global approach to clinical development allows for broader patient access and diverse data collection. They may also pursue global partnerships for drug development and commercialization.

Street Address:

75 Hayden Avenue, Suite C-1

City:

Lexington

State/Province:

MA

Country:

USA

Leap Therapeutics's Global Presence

Buying Intent Signals for Leap Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Executive Team of Leap Therapeutics

As of April 2025, Leap Therapeutics' leadership includes:

Douglas E. Onsi - President & Chief Executive Officer
Cynthia Sirard, M.D. - Chief Medical Officer
Richard Termini - Chief Financial Officer and Treasurer
Jason Baum, Ph.D. - Senior Vice President, Head of Translational Medicine

Investors of Leap Therapeutics

Leap Therapeutics has been backed by several prominent investors over the years, including:

Perceptive Advisors LLC
HealthCor Management, L.P.
Baker Bros. Advisors LP
Boxer Capital, LLC
Vivo Capital

Executive New Hires/Exits in the Last 12 Months

Hire1
Exits0

In the last 12 months (from approximately mid-2023 to mid-2024), Leap Therapeutics notably strengthened its executive team with the appointment of a new Chief Financial Officer. No significant executive departures were publicly announced during this period.

New Appointments:

Richard Termini, Richard Termini joined Leap Therapeutics as Chief Financial Officer and Treasurer, enhancing the company's financial leadership.

Technology (Tech Stack) used by Leap Therapeutics

Discover the tools Leap Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Leap Therapeutics Email Formats and Examples

Leap Therapeutics appears to utilize a common corporate email format, typically combining the employee's first initial and last name.

flast@leaptx.com

Format

jonsi@leaptx.com

Example

75%

Success rate

News and media

Business WireMay 9, 2024

Leap Therapeutics Reports First Quarter 2024 Financial Results and Recent Business Highlights

Leap Therapeutics announced its financial results for the first quarter ended March 31, 2024, and provided an update on its ongoing clinical programs, particularly for DKN-01 in gastroesophageal and gynecologic cancers....more

Business WireApril 8, 2024

Leap Therapeutics Presents New DKN-01 Data at the 2024 AACR Annual Meeting

Leap Therapeutics presented new clinical data on DKN-01 at the American Association for Cancer Research (AACR) Annual Meeting 2024. The data included findings from the DeFianCe study in colorectal cancer and the Part C study in gastric or gastroesophageal junction cancer....more

GlobeNewswireAugust 2, 2023

Leap Therapeutics Appoints Richard Termini as Chief Financial Officer

Leap Therapeutics announced the appointment of Richard Termini as its new Chief Financial Officer and Treasurer, effective August 1, 2023. Mr. Termini brings over 20 years of financial leadership experience in the biopharmaceutical industry....more

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