What Does Kaleido Biosciences Do?

Total employees10
HeadquartersBedford
Founded2015

Kaleido Biosciences, Inc. was a clinical-stage biotechnology company focused on leveraging the therapeutic potential of the microbiome to treat a variety of diseases, including those involving the immune system and metabolism. The company's approach involved identifying and developing novel Microbiome Metabolic Therapies (MMTs™). In April 2022, Kaleido Biosciences filed for Chapter 11 bankruptcy and subsequently sold substantially all of its assets, effectively ceasing its primary operations. Prior to this, it was actively engaged in research and clinical trials for conditions such as Urea Cycle Disorders and Ulcerative Colitis.

Where Is Kaleido Biosciences's Headquarters?

HQ Function

Formerly served as the primary center for research and development, clinical operations, and corporate administration for the company's microbiome therapeutic programs.

Notable Features:

The facility likely housed advanced laboratory spaces for microbiome research, analytical chemistry, and process development, alongside typical corporate office amenities. Specific architectural highlights are not widely publicized for a company of its nature and lifespan.

Work Culture:

As a clinical-stage biotech, the work culture was likely characterized by a fast-paced, innovative, and science-driven environment. Teams would have been focused on research breakthroughs, clinical trial execution, and regulatory milestones. This is no longer applicable as operations have ceased.

HQ Significance:

The headquarters was significant as the nerve center for Kaleido's pioneering efforts in Microbiome Metabolic Therapies. It was where their scientific strategy was developed and executed before the company's bankruptcy.

Values Reflected in HQ: The headquarters would have aimed to reflect values such as scientific innovation, collaboration, and a commitment to patient health, common in the biopharmaceutical industry, before its operational wind-down.

Location:

Kaleido Biosciences was primarily U.S.-based, with its operations centered in Massachusetts. While its clinical trials might have involved sites or collaborations internationally, as is common in drug development, the company did not maintain a significant network of international offices. All global activities ceased with its bankruptcy and asset sale in 2022.

Street Address:

18 Crosby Drive

City:

Bedford

State/Province:

MA

Country:

USA

Where Else Does Kaleido Biosciences Operate Around the World?

No additional office locations available.

Buying Intent Signals for Kaleido Biosciences

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading Kaleido Biosciences? Meet the Executive Team

As of April 2025, Kaleido Biosciences' leadership includes:

Daniel L. Menichella - Former President and Chief Executive Officer
William T. (Bill) Duke - Former Chief Financial Officer
Johan van Hylckama Vlieg - Former Chief Scientific Officer
Katharine Knobil, M.D. - Former Chief Medical Officer and Head of R&D

Who's Investing in Kaleido Biosciences?

Kaleido Biosciences has been backed by several prominent investors over the years, including:

Flagship Pioneering
Invus
Rock Springs Capital
Fidelity Management & Research Company
Abu Dhabi Investment Authority
other institutional investors

What Leadership Changes Has Kaleido Biosciences Seen Recently?

Hire0
ExitsAll key executives effectively exited with the company's wind-down.

Significant executive changes occurred leading up to and during Kaleido Biosciences' Chapter 11 bankruptcy filing in April 2022 and subsequent asset sale. Most, if not all, executives departed as operations ceased. There have been no new executive hires in the last 12 months as the company is no longer operational.

Departures

Daniel L. Menichella, Departed following the company's Chapter 11 bankruptcy filing.
William T. (Bill) Duke, Departed following the company's Chapter 11 bankruptcy filing.
Johan van Hylckama Vlieg, Departed following the company's Chapter 11 bankruptcy filing.
Katharine Knobil, M.D., Departed following the company's Chapter 11 bankruptcy filing.

What Technology (Tech Stack) Is Used byKaleido Biosciences?

Discover the tools Kaleido Biosciences uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Kaleido Biosciences Email Formats and Examples

Based on common corporate email patterns for companies of its type and era, Kaleido Biosciences likely used formats such as first initial followed by last name, or first name.last name. As the company has ceased operations, these email addresses are no longer active.

[first_initial][last]@kaleido.com or [first].[last]@kaleido.com

Format

jdoe@kaleido.com or jane.doe@kaleido.com

Example

0%

Success rate

What's the Latest News About Kaleido Biosciences?

BioSpaceApril 28, 2022

Kaleido Biosciences, Inc. Sells Assets to Microbiome ECI, LLC Following Bankruptcy

Kaleido Biosciences, Inc. announced that Microbiome ECI, LLC, an affiliate of JATT Acquisition Corp (NYSE: JATT), was the successful bidder to acquire substantially all of the assets of Kaleido in an auction held on April 26, 2022. The sale was part of Kaleido's Chapter 11 bankruptcy proceedings....more

GlobeNewswireApril 8, 2022

Kaleido Biosciences, Inc. Files for Chapter 11 Bankruptcy

Kaleido Biosciences, Inc. announced it was ceasing development of its lead candidate KB109 for COVID-19 and that the company filed a voluntary petition for relief under Chapter 11 of the Bankruptcy Code to pursue a sale of its assets....more

Fierce BiotechFebruary 15, 2022

Kaleido Biosciences, Inc. Lays Off Staff and Explores Strategic Alternatives

Kaleido Biosciences announced a workforce reduction and a halt to its ulcerative colitis program as it explored strategic alternatives due to a cash crunch, foreshadowing its later bankruptcy....more

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