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IsoPlexis Inc. was a life science technology company dedicated to accelerating the development of curative medicines by providing advanced solutions for single-cell functional proteomics. Their platforms, notably the IsoLight and IsoSpark systems, were designed to reveal unique cellular activity and functional biological insights critical for research in cancer immunology, cell and gene therapy, inflammation, and neurology. In March 2023, IsoPlexis was acquired by Berkeley Lights, which subsequently rebranded as PhenomeX. PhenomeX, along with the IsoPlexis technology portfolio, was then acquired by Bruker Corporation in late 2023. IsoPlexis's innovative technology continues to contribute to advancements in cellular analysis under Bruker's ownership.
This facility was the nerve center for IsoPlexis, housing its core research and development activities, manufacturing of its proteomic analysis instruments and reagent kits, and all corporate administrative functions.
The headquarters was equipped with specialized laboratory spaces for advanced biological research, engineering workshops for instrument prototyping and assembly, and likely cleanroom environments essential for producing sensitive biotech consumables. Specific architectural highlights are not publicly detailed, but functionality for life science operations was paramount.
The work culture at IsoPlexis's Branford HQ was likely characterized by a dynamic, mission-driven, and collaborative atmosphere, typical of innovative biotech firms. Employees were focused on cutting-edge scientific challenges and translating research into impactful products for the life sciences industry.
Branford served as the birthplace and operational hub for IsoPlexis's pioneering single-cell proteomic technologies, including the development and launch of its flagship IsoLight and IsoSpark systems. Its location within a biotech cluster provided access to talent and collaborative opportunities.
Prior to its acquisition, IsoPlexis Inc. established a global presence, supporting its customer base across North America, Europe, and Asia-Pacific. This was achieved through a network of direct sales teams, field application specialists, and service engineers. The company's operations were focused on delivering its advanced single-cell analysis instruments, consumable kits, and software solutions to academic research institutions, biopharmaceutical companies, and contract research organizations worldwide. This global reach was instrumental in driving the adoption of its technology for applications in immunotherapy, cell and gene therapy, inflammation research, and neurology.
35 NE Industrial Rd
Branford
Connecticut
USA
Address: [Specific street address not readily available, typically located in a major business or technology park catering to life sciences.]
To expand IsoPlexis's market presence in Asia, provide localized technical expertise and support, and facilitate collaborations with research institutions and biopharmaceutical companies in China and surrounding countries.
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As of April 2025, IsoPlexis' leadership includes:
IsoPlexis has been backed by several prominent investors over the years, including:
IsoPlexis Inc. was acquired by Berkeley Lights (later PhenomeX) in March 2023, and PhenomeX was subsequently acquired by Bruker in late 2023. Consequently, executive movements for the independent 'IsoPlexis Inc.' entity did not occur in the last 12 months as the company was absorbed. Major leadership transitions occurred surrounding these acquisitions.
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Historically, IsoPlexis Inc. likely utilized common corporate email address structures. The primary domain was @isoplexis.com. Given the company's acquisition, these email formats are no longer active for 'IsoPlexis Inc.' as an independent entity.
Common historical formats included [first_initial][last]@isoplexis.com (e.g., jsmith@isoplexis.com) and [first].[last]@isoplexis.com (e.g., john.smith@isoplexis.com).
Format
jsmith@isoplexis.com
Example
75 (estimated historical likelihood of one of these formats being correct for IsoPlexis Inc. prior to acquisition; current deliverability to @isoplexis.com addresses for former personnel is effectively 0).%
Success rate
GlobeNewswire • March 1, 2023
Berkeley Lights, Inc. (Nasdaq: BLI) announced the successful completion of its acquisition of IsoPlexis Corporation (Nasdaq: ISO). The merger aimed to combine two leading platforms in functional cell biology to create a comprehensive offering for cell-based product development and research. Berkeley Lights subsequently rebranded to PhenomeX....more
Bruker Corporation Press Release • October 2, 2023
Bruker Corporation (Nasdaq: BRKR) announced the successful completion of its acquisition of PhenomeX (Nasdaq: CELL), formerly Berkeley Lights. This acquisition includes the IsoPlexis single-cell proteomics technology, significantly enhancing Bruker's portfolio and capabilities in life science research and cellular analysis....more
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