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F-Cubed (F³) Female Founders Fund is a dedicated initiative by F-Prime Capital, a global venture capital firm, focused on fostering a more equitable and inclusive venture capital ecosystem. Launched to formalize F-Prime's long-standing commitment to backing female entrepreneurs, F-Cubed provides early-stage capital, strategic mentorship, and access to F-Prime’s extensive global network. The fund primarily targets visionary female founders who are building transformative companies in the technology and healthcare sectors. F-Cubed aims to empower these entrepreneurs to scale their businesses, achieve their full potential, and drive innovation, thereby addressing the funding gap for female-led startups.
Serves as the primary operational base for F-Prime Capital, including the F-Cubed Female Founders Fund initiative. Responsibilities include investment sourcing and decision-making, portfolio company support, and strategic operations for the fund.
Located in Kendall Square, a vibrant innovation district, providing proximity to leading tech and biotech companies, research institutions, and startups. The office is a modern workspace designed for collaboration.
The culture at F-Prime, and by extension for F-Cubed, is research-intensive, collaborative, and deeply supportive of entrepreneurs. There's a strong emphasis on long-term partnerships and a commitment to fostering diversity and inclusion within the venture ecosystem.
Cambridge, MA, is a global hub for technology and life sciences innovation. This strategic location allows F-Prime and the F-Cubed initiative to be at the forefront of emerging trends and to maintain close relationships with the entrepreneurial community.
While headquartered in Cambridge, MA, the F-Cubed Female Founders Fund leverages F-Prime Capital's global presence, particularly in North America and Europe. This allows the initiative to source, invest in, and support female-led startups internationally, with teams on the ground in key innovation hubs. The fund supports global functions such as deal sourcing, due diligence, portfolio management, and provides access to an international network of experts and partners for its portfolio companies.
One Main Street, 13th Floor
Cambridge
MA
USA
Address: 25 Cannon Street, London, EC4M 5TA, UK
To extend F-Prime's global reach and provide localized support to portfolio companies and female entrepreneurs within the European innovation ecosystem.
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As of April 2025, Female Founders Fund' leadership includes:
Female Founders Fund has been backed by several prominent investors over the years, including:
No major public announcements of executive hires or exits at the Managing Partner level directly tied to leading the F-Cubed initiative or F-Prime Capital's top leadership have been identified in the past 12 months. The firm generally maintains a stable leadership team focused on its investment strategies, including the F-Cubed program.
Discover the tools Female Founders Fund uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
F-Prime Capital, which runs the F-Cubed initiative, commonly uses the email format [first_initial][last]@fprimecapital.com. This format is typical for reaching out to partners and team members at the firm.
[first_initial][last]@fprimecapital.com
Format
jdoe@fprimecapital.com
Example
75%
Success rate
Fierce Biotech / Company Announcements • November 15, 2023
F-Prime Capital was a key investor in Portal Bio Ltd.'s significant funding round. Portal Bio, led by CEO Penny McCormick, is developing needle-free drug delivery systems. This investment aligns with F-Prime's F-Cubed initiative's goal of backing innovative companies with female leadership in the healthcare sector....more
Axios Pro • March 1, 2022
F-Prime Capital, the venture capital firm affiliated with Fidelity Investments, launched its F-Cubed (Female Founders Fund) initiative, committing an initial $25 million to invest in early-stage companies led by female entrepreneurs. The program aims to address funding disparities and provide dedicated support to women building transformative businesses in tech and life sciences....more
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