What Does EnClear Therapies Do?

Total employees12
HeadquartersCambridge
Founded2018

enClear Therapies is a pioneering clinical-stage biopharmaceutical company focused on developing transformative, disease-modifying therapies for complex neurodegenerative diseases. Their core mission is to address the significant unmet medical needs of patients suffering from conditions such as Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease, and Parkinson's disease. The company's innovative approach centers on clearing toxic proteins from the brain's glymphatic system using their proprietary EnClear-Clin™ platform technology, which involves a novel closed-loop cerebrospinal fluid (CSF) circulation system. By directly targeting the removal of these harmful proteins, enClear aims to halt or reverse disease progression, offering new hope to patients and their families.

Where Is EnClear Therapies's Headquarters?

HQ Function

The Cambridge headquarters serves as the central hub for enClear Therapies' research and development, clinical operations, corporate strategy, and administrative functions.

Notable Features:

Situated in Kendall Square, the facility benefits from proximity to leading academic institutions, research organizations, and a dense network of biotech and pharmaceutical companies. It likely features modern laboratory and office spaces designed to foster collaboration and cutting-edge scientific research.

Work Culture:

The work culture at enClear Therapies is characterized by a strong emphasis on scientific excellence, innovation, collaboration, and a patient-centric approach. Employees are typically mission-driven, dedicated to making a significant impact in the field of neurodegenerative diseases.

HQ Significance:

The Cambridge headquarters is critical to enClear's operations, providing access to top-tier talent, scientific collaborators, and resources essential for advancing its novel therapeutic platform and clinical programs.

Values Reflected in HQ: The headquarters' location and design reflect enClear's commitment to innovation, scientific rigor, and collaboration in its pursuit of breakthrough therapies.

Location:

While enClear Therapies' physical headquarters is in the US, its mission and operations have a global outlook. The company supports functions such as international clinical trial site management, collaborations with researchers and institutions worldwide, and aims for future global commercialization of its therapies to address neurodegenerative diseases that affect populations across the globe. They engage with the international scientific community to advance their research and development efforts.

Street Address:

245 First Street, Suite 1800

City:

Cambridge

State/Province:

MA

Country:

USA

Where Else Does EnClear Therapies Operate Around the World?

Information Not Publicly Available

Address: N/A

N/A

Buying Intent Signals for EnClear Therapies

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Who's Leading EnClear Therapies? Meet the Executive Team

As of April 2025, EnClear Therapies' leadership includes:

Anthony J. DePasqua - President & Chief Executive Officer
William S. Koster, Ph.D. - Chief Scientific Officer
Richard C. Wilson - Chief Financial Officer
Samantha E. Hutten, Ph.D. - Senior Vice President, Head of Translational Medicine

Who's Investing in EnClear Therapies?

EnClear Therapies has been backed by several prominent investors over the years, including:

Morningside Ventures
Dolby Family Ventures
Alzheimer's Drug Discovery Foundation (ADDF)

What Leadership Changes Has EnClear Therapies Seen Recently?

Hire0
Exits0

enClear Therapies has focused on strengthening its leadership and governance. In the past 12 months (ending July 2024), a key development was the appointment of Dr. Paul L. Berns to its Board of Directors, bringing extensive biopharma experience. No major C-suite executive hires or departures have been publicly announced during this specific period.

New Appointments:

Dr. Paul L. Berns, Dr. Paul L. Berns joined the Board of Directors, bringing over 30 years of biopharmaceutical industry experience.

What Technology (Tech Stack) Is Used byEnClear Therapies?

Discover the tools EnClear Therapies uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

EnClear Therapies Email Formats and Examples

Based on common patterns in the biopharmaceutical industry and data from professional networking platforms, enClear Therapies likely uses a standardized email format. The most probable primary format is [first_initial][last_name]@enclear-therapies.com.

[first_initial][last]@enclear-therapies.com

Format

adepasqua@enclear-therapies.com

Example

75%

Success rate

What's the Latest News About EnClear Therapies?

Business WireMarch 20, 2024

enClear Therapies Appoints Biopharma Veteran Dr. Paul L. Berns to its Board of Directors

enClear Therapies announced the appointment of Paul L. Berns to its Board of Directors. Dr. Berns brings over three decades of experience in the biopharmaceutical sector, enhancing the company's strategic leadership....more

Business WireJanuary 18, 2024

enClear Therapies Announces First Patient Dosed in Phase 1 Clinical Trial of EnCL-001 for the Treatment of Amyotrophic Lateral Sclerosis (ALS)

enClear Therapies reported the dosing of the first patient in its Phase 1 clinical study of EnCL-001, a novel therapy candidate for ALS. The study aims to evaluate the safety, tolerability, and pharmacokinetics of EnCL-001....more

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