What Does Duke Clinical Research Institute Do?

Total employees1076
HeadquartersDurham
Founded1969

The Duke Clinical Research Institute (DCRI), part of Duke University School of Medicine, is the world's largest academic research organization (ARO). It uniquely combines the clinical expertise and academic leadership of a premier institution with the full-service operational capabilities of a contract research organization (CRO). DCRI is dedicated to developing and sharing knowledge that improves the care of patients globally through pioneering clinical research. Its scope encompasses a wide array of therapeutic areas, all phases of clinical trials, outcomes research, health services research, and patient safety initiatives.

Where Is Duke Clinical Research Institute's Headquarters?

HQ Function

Serves as the central operational and intellectual hub for DCRI's global clinical research activities, housing faculty, researchers, biostatisticians, data scientists, and administrative staff who design, manage, and analyze clinical trials and health studies.

Notable Features:

State-of-the-art research facilities, advanced data analytics infrastructure, collaborative workspaces designed to foster interdisciplinary teamwork. The North Pavilion building is a key facility specifically developed for research entities within Duke Health.

Work Culture:

A highly collaborative, intellectually stimulating, and mission-driven environment. Emphasizes scientific rigor, innovation, mentorship, and a commitment to improving patient health worldwide. Strong interdisciplinary teamwork is a hallmark.

HQ Significance:

As the nerve center for the world's largest ARO, the DCRI headquarters is instrumental in conducting landmark clinical trials that shape medical practice and health policy globally. Its co-location with Duke University and Duke Health fosters seamless translation of research into clinical care.

Values Reflected in HQ: The headquarters' design and operation reflect DCRI's core values of excellence, integrity, collaboration, innovation, and patient-centeredness, providing an environment conducive to high-impact research and learning.

Location:

While headquartered in Durham, NC, the Duke Clinical Research Institute (DCRI) operates on a global scale, conducting and coordinating clinical trials and research studies in numerous countries across six continents. Its international footprint is established through a vast network of collaborating research sites, investigators, academic institutions, and healthcare systems worldwide. DCRI provides comprehensive global support for multinational studies, including study design, site identification and management, patient recruitment, global data collection and harmonization, regulatory expertise, and safety monitoring, all aimed at improving health outcomes for diverse populations around the world.

Street Address:

2400 Pratt Street (North Pavilion)

City:

Durham

State/Province:

North Carolina

Country:

USA

Where Else Does Duke Clinical Research Institute Operate Around the World?

Durham, North Carolina, USA

Address: 200 Morris Street (Durham Centre), Durham, NC 27701

To provide flexible, modern office space for various research support functions, facilitating efficient project execution and collaboration among diverse teams, while being strategically located within the vibrant research community of Durham.

Durham, North Carolina, USA

Address: 300 West Morgan Street (Durham ID), Durham, NC 27701

To integrate DCRI's data-intensive research arms within a hub of innovation, allowing for synergies with tech companies and startups, and to provide specialized environments for data analytics and computational research.

Buying Intent Signals for Duke Clinical Research Institute

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Notable news
Hiring actively
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Who's Leading Duke Clinical Research Institute? Meet the Executive Team

As of April 2025, Duke Clinical Research Institute' leadership includes:

Adrian F. Hernandez, MD, MHS - Executive Director, Duke Clinical Research Institute; Vice Dean, Duke University School of Medicine
Susanna Naggie, MD, MHS - Director of Clinical Research, DCRI; Vice Dean for Clinical Research, Duke University School of Medicine
Kevin Anstrom, PhD - Director, Biostatistics Center, DCRI; Professor of Biostatistics and Bioinformatics
Eric Peterson, MD, MPH - Associate Director, Research, DCRI; Fred Cobb, MD, Distinguished Professor of Medicine in Cardiology
Wendy K. D. Selig - Chief Information Officer
Frank Rockhold, PhD - Professor of Biostatistics and Bioinformatics; Senior Advisor for Data Science Initiatives

Who's Investing in Duke Clinical Research Institute?

Duke Clinical Research Institute has been backed by several prominent investors over the years, including:

Duke University School of Medicine
National Institutes of Health (NIH)
Other U.S. Government Agencies (e.g., FDA, AHRQ, PCORI)
Pharmaceutical, Biotechnology, and Medical Device Industry Sponsors
Foundations and Non-profit Health Organizations
Professional Societies

What Leadership Changes Has Duke Clinical Research Institute Seen Recently?

Hire0
Exits0

Specific executive hire and exit announcements for the Duke Clinical Research Institute are typically managed within the broader Duke University Health System or School of Medicine communications framework. Publicly available information on distinct DCRI executive team changes within the last 12 months is limited, often reflecting academic appointments or internal role shifts rather than corporate-style executive moves. DCRI generally maintains strong leadership continuity.

What Technology (Tech Stack) Is Used byDuke Clinical Research Institute?

Discover the tools Duke Clinical Research Institute uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Duke Clinical Research Institute Email Formats and Examples

Email addresses for individuals at the Duke Clinical Research Institute generally adhere to the standard email format used by Duke University and Duke Health. The most prevalent format is [first_name].[last_name]@duke.edu. Some variations might exist, such as using a middle initial or a slightly different convention for common names.

[first_name].[last_name]@duke.edu

Format

jane.doe@duke.edu

Example

90%

Success rate

What's the Latest News About Duke Clinical Research Institute?

dcri.orgApril 29, 2024

DCRI Convenes First Summit for NIH AIM-AHEAD Program to Advance Health Equity Through Artificial Intelligence and Machine Learning

The DCRI hosted the inaugural summit for the NIH's Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD) program. The event brought together national experts to strategize on leveraging AI/ML to reduce health disparities and promote equity in healthcare research and application....more

Duke TodayApril 7, 2024

Duke-Led Study: Common Heart Failure Drug Does Not Improve Outcomes for Common Type of Heart Failure

A large-scale international clinical trial, TRANSFORM-HF, co-led by DCRI's Executive Director Dr. Adrian Hernandez, found that the diuretic torsemide was not superior to the older, less expensive furosemide in reducing deaths or hospitalizations for patients with heart failure. The findings were presented at the American College of Cardiology's Annual Scientific Session and published in JAMA....more

dcri.orgNovember 13, 2023

ADAPTABLE Trial Results Published in New England Journal of Medicine

The results of the landmark ADAPTABLE aspirin study, a pragmatic trial coordinated by DCRI and funded by PCORI, were published in the New England Journal of Medicine. The study compared two different doses of aspirin for secondary prevention of cardiovascular events, providing crucial evidence for patient and clinician decision-making....more

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