Cyteir Therapeutics, Inc. was a clinical-stage biopharmaceutical company dedicated to the discovery and development of next-generation synthetically lethal therapies to treat cancer. Its lead drug candidate was CYT-0851, an oral, once-daily, rationally designed, selective inhibitor of monocarboxylate transporters. In September 2023, Cyteir announced a plan to cease further drug development, wind down its operations, and delist from Nasdaq, following a strategic review and challenges in its clinical programs. The company is currently in the process of liquidation and dissolution.
The headquarters served as the central hub for Cyteir's research and development, clinical operations, and corporate administration during its operational phase.
The facility likely comprised standard biopharmaceutical office and laboratory space within a larger office park, designed to support research and development activities. Specific architectural highlights are not widely publicized.
Prior to its wind-down, Cyteir likely fostered a work culture centered on scientific innovation, collaboration, and a dedicated pursuit of oncology breakthroughs, typical of clinical-stage biotechnology firms. The environment would have been dynamic and results-oriented.
The Lexington headquarters was significant as the operational base from which Cyteir advanced its pipeline of DNA damage response inhibitors into clinical trials.
As a US-based clinical-stage company, Cyteir Therapeutics's operations were primarily focused in the United States, particularly for its research, development, and clinical trial management. Its direct operational presence was largely domestic before it began wind-down procedures.
128 Spring Street, Building A, Suite 500
Lexington
MA
USA
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As of April 2025, Cyteir Therapeutics' leadership includes:
Cyteir Therapeutics has been backed by several prominent investors over the years, including:
Following the announcement in September 2023 to wind down operations, Cyteir Therapeutics experienced significant executive departures. John F. Thero, a board member, assumed key executive roles to manage the company's wind-down and dissolution.
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Cyteir Therapeutics likely used a common corporate email format. Based on publicly available information, the pattern [first_initial][last]@cyteir.com was in use. Due to the company's wind-down, email addresses may no longer be actively monitored.
[first_initial][last]@cyteir.com
Format
mrenschler@cyteir.com
Example
20%
Success rate
GlobeNewswire • September 7, 2023
Cyteir Therapeutics, Inc. announced that following a comprehensive assessment of its strategic options, its Board of Directors has approved a plan to cease further drug development, wind down its operations, delist its common stock from The Nasdaq Stock Market LLC, and deregister its common stock....more
SEC Edgar • March 29, 2024
Cyteir Therapeutics filed a preliminary proxy statement for a special meeting of stockholders to vote on a Plan of Liquidation and Dissolution. This plan outlines the process for distributing remaining assets to shareholders after settling liabilities as the company proceeds with its wind-down....more
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