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Cyteir Therapeutics's Overview

Total employees3
HeadquartersLexington
Founded2012

Cyteir Therapeutics, Inc. was a clinical-stage biopharmaceutical company dedicated to the discovery and development of next-generation synthetically lethal therapies to treat cancer. Its lead drug candidate was CYT-0851, an oral, once-daily, rationally designed, selective inhibitor of monocarboxylate transporters. In September 2023, Cyteir announced a plan to cease further drug development, wind down its operations, and delist from Nasdaq, following a strategic review and challenges in its clinical programs. The company is currently in the process of liquidation and dissolution.

Where is Cyteir Therapeutics's Headquarters?

HQ Function

The headquarters served as the central hub for Cyteir's research and development, clinical operations, and corporate administration during its operational phase.

Notable Features:

The facility likely comprised standard biopharmaceutical office and laboratory space within a larger office park, designed to support research and development activities. Specific architectural highlights are not widely publicized.

Work Culture:

Prior to its wind-down, Cyteir likely fostered a work culture centered on scientific innovation, collaboration, and a dedicated pursuit of oncology breakthroughs, typical of clinical-stage biotechnology firms. The environment would have been dynamic and results-oriented.

HQ Significance:

The Lexington headquarters was significant as the operational base from which Cyteir advanced its pipeline of DNA damage response inhibitors into clinical trials.

Values Reflected in HQ: The HQ's location in a prominent biotech cluster (Lexington, MA) reflected Cyteir's commitment to innovation, access to talent, and collaboration within the life sciences ecosystem during its operational period.

Location:

As a US-based clinical-stage company, Cyteir Therapeutics's operations were primarily focused in the United States, particularly for its research, development, and clinical trial management. Its direct operational presence was largely domestic before it began wind-down procedures.

Street Address:

128 Spring Street, Building A, Suite 500

City:

Lexington

State/Province:

MA

Country:

USA

Cyteir Therapeutics's Global Presence

Buying Intent Signals for Cyteir Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Executive Team of Cyteir Therapeutics

As of April 2025, Cyteir Therapeutics' leadership includes:

John F. Thero - Principal Executive Officer, Principal Financial Officer, and Principal Accounting Officer (overseeing wind-down)

Investors of Cyteir Therapeutics

Cyteir Therapeutics has been backed by several prominent investors over the years, including:

RA Capital Management
Novo Holdings A/S
Venrock
Lightstone Ventures
Celgene (now Bristol Myers Squibb)
DROIA Oncology Ventures
Osage University Partners
Alexandria Venture Investments

Executive New Hires/Exits in the Last 12 Months

Hire1
Exits3

Following the announcement in September 2023 to wind down operations, Cyteir Therapeutics experienced significant executive departures. John F. Thero, a board member, assumed key executive roles to manage the company's wind-down and dissolution.

Departures

Markus Renschler, M.D., Departed as President and CEO following the company's decision to wind down operations.
Ryan Conlon, Departed as CFO in connection with the company's wind-down plan.
Andrew G.S. Daniel, M.D., Departed as CMO as part of the company's wind-down process.

New Appointments:

John F. Thero, John F. Thero, a member of the Board, assumed key executive leadership responsibilities to guide Cyteir Therapeutics through its operational wind-down and dissolution process.

Technology (Tech Stack) used by Cyteir Therapeutics

Discover the tools Cyteir Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Cyteir Therapeutics Email Formats and Examples

Cyteir Therapeutics likely used a common corporate email format. Based on publicly available information, the pattern [first_initial][last]@cyteir.com was in use. Due to the company's wind-down, email addresses may no longer be actively monitored.

[first_initial][last]@cyteir.com

Format

mrenschler@cyteir.com

Example

20%

Success rate

News and media

GlobeNewswireSeptember 7, 2023

Cyteir Therapeutics Announces Plan to Wind Down Operations and Delist from Nasdaq

Cyteir Therapeutics, Inc. announced that following a comprehensive assessment of its strategic options, its Board of Directors has approved a plan to cease further drug development, wind down its operations, delist its common stock from The Nasdaq Stock Market LLC, and deregister its common stock....more

SEC EdgarMarch 29, 2024

Cyteir Therapeutics Files Preliminary Proxy Statement for Special Meeting to Approve Dissolution

Cyteir Therapeutics filed a preliminary proxy statement for a special meeting of stockholders to vote on a Plan of Liquidation and Dissolution. This plan outlines the process for distributing remaining assets to shareholders after settling liabilities as the company proceeds with its wind-down....more

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