Cubist Pharmaceuticals Inc. was a biopharmaceutical company focused on the research, development, and commercialization of novel therapies to treat serious and life-threatening infections. Prior to its acquisition by Merck & Co. in January 2015 for $9.5 billion, Cubist was recognized for its leading antibiotic, Cubicin® (daptomycin for injection), and a robust pipeline of anti-infective candidates. The company was dedicated to addressing the growing problem of antibiotic resistance and unmet medical needs in acute care settings. Its operations and portfolio are now integrated into Merck.
Served as the global headquarters, housing corporate offices, research and development laboratories, and administrative functions. It was central to Cubist's drug discovery, clinical development, and commercial strategy operations.
State-of-the-art laboratory facilities designed for antibiotic research and development, part of the dynamic biotech ecosystem in the Greater Boston area.
Known for a science-driven, innovative, and collaborative environment focused on tackling challenging infectious diseases. Employees were often mission-driven, aiming to bring life-saving therapies to patients.
The Lexington headquarters was the nerve center for Cubist's growth from a research-focused startup to a leading commercial-stage biopharmaceutical company in the anti-infectives space. Key strategic decisions and research breakthroughs originated here.
Prior to its acquisition by Merck in 2015, Cubist Pharmaceuticals was actively expanding its global presence. This was primarily driven by the commercialization of its flagship antibiotic, Cubicin®, and later Sivextro™. Key functions supported globally included establishing and managing commercial operations in North America and Europe (via its Zurich international HQ), overseeing multi-regional clinical trials for its pipeline candidates, handling regulatory submissions to health authorities worldwide (e.g., FDA, EMA), and building sales, marketing, and medical affairs capabilities in targeted international markets.
65 Hayden Avenue
Lexington
Massachusetts
U.S.A.
Address: Prime Tower, Hardstrasse 201, 8005 Zurich, Switzerland (Former International HQ)
To spearhead the expansion and commercialization of Cubist's products, such as Cubicin® and Sivextro™, across Europe and other international markets, and to manage regional partnerships and clinical development activities.
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As of April 2025, Cubist Pharmaceuticals' leadership includes:
Cubist Pharmaceuticals has been backed by several prominent investors over the years, including:
Executive changes for Cubist Pharmaceuticals as an independent entity primarily relate to the period leading up to and including its acquisition by Merck & Co. in January 2015. Post-acquisition, its leadership structure was absorbed or dissolved. Therefore, 'last 12 months' data for an independent Cubist is not applicable for new hires or exits in the conventional sense.
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Prior to its acquisition by Merck and the discontinuation of its independent operations, Cubist Pharmaceuticals likely used standard corporate email formats. The @cubist.com domain is no longer active for email communication.
[first_initial][last_name]@cubist.com (e.g., jdoe@cubist.com) and/or [first_name].[last_name]@cubist.com (e.g., jane.doe@cubist.com) were common patterns.
Format
jbonney@cubist.com
Example
0 (Domain inactive post-acquisition)%
Success rate
Merck News • January 21, 2015
Merck announced the completion of its acquisition of Cubist Pharmaceuticals, Inc. for $102 per share in cash, a total transaction value of approximately $9.5 billion. The acquisition significantly bolstered Merck’s hospital acute care portfolio, particularly in anti-infectives....more
Fierce Biotech / FDA • June 20, 2014
Cubist Pharmaceuticals announced that the U.S. Food and Drug Administration (FDA) approved SIVEXTRO™ (tedizolid phosphate) for the treatment of adult acute bacterial skin and skin structure infections (ABSSSI), strengthening its antibiotic franchise....more
PR Newswire / FDA • September 12, 2003
Cubist Pharmaceuticals received U.S. FDA approval for CUBICIN® (daptomycin for injection) for treating complicated skin and skin structure infections (cSSSI) caused by certain Gram-positive bacteria, including MRSA. This was a landmark approval for the company....more
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