Chinook Therapeutics, Inc. was a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing precision medicines for rare, severe chronic kidney diseases. Their pipeline included atrasentan, an investigational selective endothelin A receptor antagonist, and BION-1301, an investigational anti-APRIL monoclonal antibody. In August 2023, Chinook Therapeutics was acquired by Novartis for up to $3.5 billion, aiming to significantly expand Novartis's renal portfolio and leverage Chinook's expertise in kidney disease research.
Prior to its acquisition by Novartis, the Seattle headquarters served as the primary center for Chinook's corporate operations, research and development leadership, and clinical program management.
Located in the vibrant South Lake Union biotech hub, offering modern laboratory and office facilities conducive to scientific research and collaboration.
As a clinical-stage biotech, the culture likely emphasized innovation, scientific rigor, a fast-paced environment, and a strong patient-centric mission focused on kidney diseases.
The headquarters was central to Chinook's strategy and execution in developing its pipeline of kidney disease therapeutics, including its lead candidates atrasentan and BION-1301.
Prior to its acquisition by Novartis, Chinook Therapeutics' primary operational presence was in North America, with key offices in Seattle (WA, USA), Vancouver (BC, Canada), and Berkeley (CA, USA). Its clinical trials for drug candidates were conducted globally, involving trial sites in various countries to reach diverse patient populations for its rare kidney disease programs. The company's focus was on global drug development and potential commercialization.
400 Dexter Ave N, Suite 800
Seattle
WA
USA
Address: 200 Granville St, Suite 1075, Vancouver, BC V6C 1S4, Canada
Served as a key R&D and operational site in Canada, contributing to preclinical and clinical development programs.
Address: Undisclosed specific address, but a known operational site.
Contributed to the company's research capabilities, possibly leveraging the San Francisco Bay Area's rich biotech ecosystem.
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As of April 2025, Chinook Therapeutics' leadership includes:
Chinook Therapeutics has been backed by several prominent investors over the years, including:
The most significant executive changes occurred due to the acquisition by Novartis, completed in August 2023. This typically leads to the departure or transition of the acquired company's senior leadership team as it integrates into the larger organization. There is no public information on new hires or exits in the 12 months leading up to the finalization of the acquisition that were unrelated to it.
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Prior to its acquisition by Novartis, Chinook Therapeutics Inc. likely used standard corporate email formats. The most common format observed was [first_initial][last]@chinooktx.com. Post-acquisition, communications would be managed through Novartis channels and email systems.
[first_initial][last]@chinooktx.com
Format
edobmeier@chinooktx.com
Example
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Success rate
Novartis News • August 11, 2023
Novartis announced the successful completion of its acquisition of Chinook Therapeutics, Inc. The acquisition brings Chinook's late-stage assets, atrasentan and zigakibart (BION-1301), for rare, severe chronic kidney diseases to Novartis's renal portfolio....more
Chinook Therapeutics Inc. Press Release (via PR Newswire) • June 12, 2023
Chinook Therapeutics announced it entered into a definitive agreement to be acquired by Novartis. Under the terms, Novartis would acquire Chinook for $40.00 per share in cash, plus a contingent value right of up to $4.00 per share....more
Chinook Therapeutics Inc. Press Release • May 9, 2023
Chinook Therapeutics presented updated clinical data for BION-1301, an investigational anti-APRIL monoclonal antibody, demonstrating sustained reductions in IgA and Gd-IgA1 levels in patients with IgAN. These findings were shared at the European Renal Association (ERA) Congress....more
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