ChemoCentryx, Inc. was a biopharmaceutical company focused on the discovery, development, and commercialization of orally-administered therapeutics to treat autoimmune diseases, inflammatory disorders, and cancer. Its research centered on chemokine-based biology, culminating in the development of its flagship product, TAVNEOS® (avacopan), a treatment for ANCA-associated vasculitis. In October 2022, ChemoCentryx was acquired by Amgen for approximately $3.7 billion, integrating its pipeline and TAVNEOS® into Amgen's inflammation portfolio.
This facility served as the main center for ChemoCentryx's research and development, clinical trial management, and corporate administrative operations before its acquisition.
The headquarters likely included specialized laboratory facilities for drug discovery and development, alongside modern office spaces designed to foster collaboration and innovation.
The work culture at ChemoCentryx was reportedly driven by scientific innovation, a commitment to addressing unmet patient needs, and a collaborative environment focused on advancing novel therapies.
The San Carlos headquarters was crucial for ChemoCentryx's operations, including the development and initial commercialization efforts for TAVNEOS®, and its location provided access to a rich talent pool and biotech ecosystem.
Before being acquired by Amgen, ChemoCentryx established a global presence primarily through its multi-national clinical trials for its drug candidates. For its lead product, TAVNEOS® (avacopan), it forged strategic commercialization partnerships to reach patients in key international markets, including Europe, Japan, and Canada, while direct US commercialization was handled internally. Its R&D and strategic oversight remained U.S.-based. Post-acquisition, its programs and reach are now part of Amgen's global operational footprint.
835 Industrial Road, Suite 600
San Carlos
CA
USA
Address: N/A
International activities, such as clinical trials and commercial partnerships (e.g., with Vifor Pharma for TAVNEOS® in Europe and Japan), were managed from the US headquarters or through its partners, rather than dedicated ChemoCentryx international offices.
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As of April 2025, ChemoCentryx' leadership includes:
ChemoCentryx has been backed by several prominent investors over the years, including:
The most significant executive changes for ChemoCentryx as an independent entity in the 12 months prior to its acquisition in October 2022 revolved around the transition of its leadership team following the Amgen takeover. Key executives departed their roles as ChemoCentryx was integrated into Amgen. No major new external executive hires to the independent ChemoCentryx leadership team were publicly announced during this final period.
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Prior to its acquisition by Amgen in October 2022, ChemoCentryx, Inc. utilized corporate email addresses associated with its domain. The formats listed below are based on common patterns and publicly available information for ChemoCentryx as an independent company and are for historical reference, as these email addresses are no longer active for former employees.
Commonly used formats were likely [first_initial][last]@chemocentryx.com (e.g., jdoe@chemocentryx.com) or [first].[last]@chemocentryx.com (e.g., jane.doe@chemocentryx.com). Data suggests flast@chemocentryx.com was a prevalent pattern.
Format
tsmith@chemocentryx.com
Example
70%
Success rate
Amgen Newsroom • October 20, 2022
Amgen announced it successfully completed its acquisition of ChemoCentryx for $52 per share in cash, totaling an approximate enterprise value of $3.7 billion. This acquisition brought TAVNEOS® (avacopan), a first-in-class medicine for ANCA-associated vasculitis, into Amgen's portfolio, enhancing its inflammation and nephrology franchises....more
Fierce Pharma (reporting on FDA/ChemoCentryx) • October 8, 2021
The U.S. Food and Drug Administration (FDA) granted approval for ChemoCentryx's TAVNEOS™ (avacopan), an oral selective complement 5a receptor inhibitor, as an adjunctive treatment for adult patients with severe active ANCA-associated vasculitis. This approval was a major achievement for ChemoCentryx, offering a new therapeutic option for this rare autoimmune disease....more
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