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Casebia Therapeutics's Overview

Total employees1
HeadquartersCambridge
Founded2016

Casebia Therapeutics was a biotechnology company established as a joint venture between CRISPR Therapeutics and Bayer, announced in December 2015 and commencing operations in 2016. Its mission was to discover, develop, and commercialize new CRISPR/Cas9-based therapies for genetic diseases, with initial focuses on blood disorders, blindness, and cardiovascular diseases. Headquartered in Cambridge, Massachusetts, Casebia aimed to combine CRISPR Therapeutics' gene editing technology with Bayer's protein engineering expertise and disease know-how. In May 2019, CRISPR Therapeutics acquired Bayer's stake in Casebia, fully integrating its operations, research programs, and intellectual property. While Casebia Therapeutics no longer operates as an independent entity, its foundational work contributed significantly to the advancement of gene editing therapies within CRISPR Therapeutics.

Where is Casebia Therapeutics's Headquarters?

HQ Function

The headquarters served as the primary center for research and development, program management, and administrative operations for Casebia's gene editing initiatives, focusing on translating CRISPR/Cas9 technology into viable therapeutics.

Notable Features:

Located in a modern biotech facility within Kendall Square, offering state-of-the-art laboratory spaces, advanced research equipment, and collaborative work environments designed to foster innovation.

Work Culture:

As a cutting-edge research-focused biotech venture, the work culture at Casebia Therapeutics emphasized scientific excellence, innovation, rigorous collaboration, and a strong mission-driven approach to developing transformative treatments for severe genetic diseases.

HQ Significance:

The Cambridge headquarters was strategically significant due to its location in Kendall Square, providing access to world-class academic institutions (like MIT and Harvard), a rich talent pool, and a dense ecosystem of biotech companies, VCs, and research organizations, fostering collaboration and accelerating R&D.

Values Reflected in HQ: The headquarters' design and operational focus would have reflected values such as scientific pioneering, cutting-edge innovation, a commitment to quality and safety in research, and a dedicated pursuit of developing therapies for patients with unmet medical needs.

Location:

During its operation as a joint venture, Casebia Therapeutics leveraged the global research, development, and clinical expertise of its parent companies, CRISPR Therapeutics (with operations in the US and Europe) and Bayer (a global pharmaceutical company). Casebia's direct operational footprint was primarily in the United States, with its headquarters and main research facility in Cambridge, MA, and a planned research presence in San Francisco, CA. Following its integration, its programs and intellectual property became part of CRISPR Therapeutics' global R&D pipeline and strategy.

Street Address:

100 Binney Street, Suite 600 (Primary operational address; also closely associated with CRISPR Therapeutics' facilities such as 610 Main Street)

City:

Cambridge

State/Province:

Massachusetts

Country:

USA

Casebia Therapeutics's Global Presence

San Francisco, California, USA

Address: Specific address not publicly detailed; likely a dedicated research site or co-located within Bayer's West Coast facilities.

To tap into the strong biotechnology ecosystem of the San Francisco Bay Area, access specialized talent in protein engineering and preclinical development, and facilitate collaboration with Bayer's West Coast research infrastructure.

Buying Intent Signals for Casebia Therapeutics

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Executive Team of Casebia Therapeutics

As of April 2025, Casebia Therapeutics' leadership includes:

James W. Burns, Ph.D. - Former President and Chief Executive Officer
Andrew Schiermeier, Ph.D. - Former Chief Operating Officer
Ellen Hukkelhoven, Ph.D. - Former Vice President, Program and Alliance Management

Investors of Casebia Therapeutics

Casebia Therapeutics has been backed by several prominent investors over the years, including:

CRISPR Therapeutics (Co-founder, later sole owner)
Bayer (Co-founder, divested stake in 2019)

Executive New Hires/Exits in the Last 12 Months

Hire0
Exits0

Casebia Therapeutics was fully integrated into CRISPR Therapeutics in mid-2019. Consequently, there have been no executive hires or exits specifically for Casebia Therapeutics as an independent entity in the last 12 months. Relevant news primarily pertains to its formation, key appointments during its operational period, or its integration.

Technology (Tech Stack) used by Casebia Therapeutics

Discover the tools Casebia Therapeutics uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Casebia Therapeutics Email Formats and Examples

During its operational period (2016-2019), Casebia Therapeutics likely used a standard corporate email format. As the company was integrated into CRISPR Therapeutics and its domain (casebia.com) is no longer active for email, these formats are historical.

[first_initial][last]@casebia.com or [first].[last]@casebia.com

Format

jdoe@casebia.com or jane.doe@casebia.com

Example

5%

Success rate

News and media

CRISPR Therapeutics Press ReleaseMay 30, 2019

CRISPR Therapeutics Acquires Bayer’s Stake in Casebia Therapeutics

CRISPR Therapeutics announced it has acquired Bayer’s 50% stake in their joint venture, Casebia Therapeutics. This transaction gives CRISPR Therapeutics full operational control and decision making for Casebia’s programs, intellectual property and team, which will be fully integrated into CRISPR Therapeutics....more

Business Wire (CRISPR Therapeutics)December 21, 2015

CRISPR Therapeutics and Bayer Launch Joint Venture Casebia Therapeutics to Develop Novel Therapeutics for Blood Disorders, Blindness and Congenital Heart Disease

CRISPR Therapeutics and Bayer AG today announced the launch of Casebia Therapeutics (Casebia), a joint venture (JV) to discover, develop and commercialize new breakthrough therapeutics to cure blood disorders, blindness, and congenital heart disease. Bayer will make a $300M equity investment in CRISPR Therapeutics. Bayer will provide a minimum of $335M to the JV over the next five years....more

CRISPR Therapeutics Press ReleaseApril 12, 2016

Casebia Therapeutics Names James W. Burns, Ph.D. as President and Chief Executive Officer

Casebia Therapeutics, the joint venture founded by Bayer and CRISPR Therapeutics, today announced the appointment of James (Jim) W. Burns, Ph.D., as its President and Chief Executive Officer. Dr. Burns was formerly Head of Drug Discovery and Genzyme Sanofi and brings over 30 years of R&D leadership experience....more

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