Ayala Pharmaceuticals, Inc. was a clinical-stage oncology company focused on developing and commercializing small molecule therapeutics for patients suffering from Cancers with Upregulated Notch Pathway Signaling. The company primarily targeted rare and aggressive cancers. Its lead product candidate was AL101 for adenoid cystic carcinoma (ACC). In January 2023, Advaxis, Inc. completed a reverse merger with the original Ayala Pharmaceuticals (a privately held Israeli company), and the combined entity continued as Ayala Pharmaceuticals, Inc. (NASDAQ: AYLA). Subsequently, in October 2023, Ayala Pharmaceuticals, Inc. merged with Immunome, Inc. (NASDAQ: IMNM), with the combined company operating under the Immunome name. This profile reflects Ayala Pharmaceuticals prior to its merger with Immunome.
Served as the principal executive offices, overseeing corporate strategy, clinical development programs, financial operations, and investor relations for the publicly traded entity.
The facility was a modern office space suited for a biotech company's corporate and administrative functions. Specific architectural highlights are not widely publicized, but it was part of a corporate park environment.
As a clinical-stage oncology company, the culture likely emphasized innovation, scientific rigor, patient-centricity, and collaboration. Given its M&A activities, adaptability and a results-driven approach were also probable characteristics.
This headquarters was significant as it represented the U.S. base of operations for Ayala Pharmaceuticals, Inc. following its strategic merger with Advaxis, centralizing its leadership and efforts to advance its oncology pipeline in the U.S. market.
Prior to its merger with Immunome, Ayala Pharmaceuticals had a primary presence in the United States (corporate headquarters, clinical trial operations) and Israel (significant research and development activities). Its clinical trials were also conducted internationally across various regions as needed for patient recruitment and regulatory purposes.
305 College Road East
Princeton
New Jersey
USA
Address: Weizmann Science Park, P.O.B. 4047, Ness Ziona 7414001, Israel (Address for original Ayala Pharmaceuticals, maintained as R&D site)
Focused on drug discovery, preclinical research, and development activities, particularly for its Notch pathway signaling inhibitors.
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As of April 2025, Ayala Pharmaceuticals, Inc.' leadership includes:
Ayala Pharmaceuticals, Inc. has been backed by several prominent investors over the years, including:
The executive team of Ayala Pharmaceuticals, Inc. was largely formed in January 2023 following the merger with Advaxis. The most significant executive changes occurred in October 2023 when Ayala Pharmaceuticals merged with Immunome, Inc., leading to the dissolution of the Ayala-specific executive roles as the company integrated into Immunome.
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As Ayala Pharmaceuticals, Inc. has merged with Immunome, Inc., and its former domain (ayalapharma.com) may be inactive, historical email formats are no longer in use. For companies in the biopharmaceutical sector, common email patterns often include variations of first name, last name, and initial.
Common historical patterns might have included: [first_initial][last_name]@ayalapharma.com or [first_name].[last_name]@ayalapharma.com
Format
example: jdoe@ayalapharma.com or john.doe@ayalapharma.com (These are illustrative examples of past potential formats and are not active)
Example
0 (Historical email addresses at @ayalapharma.com are unlikely to be deliverable due to the company's merger and domain status)%
Success rate
GlobeNewswire • October 25, 2023
Immunome, Inc. announced the completion of its merger with Ayala Pharmaceuticals, Inc. The combined company will operate under the Immunome name and focus on advancing Immunome's pipeline of targeted cancer therapies. Ayala common stock ceased trading on Nasdaq....more
GlobeNewswire • July 17, 2023
Immunome and Ayala Pharmaceuticals announced they entered into a definitive merger agreement. The combined company was to focus on advancing Immunome’s pipeline of novel antibody-drug conjugates (ADCs) and targeted cancer therapies....more
BioSpace • January 25, 2023
Ayala Pharmaceuticals announced the completion of the merger whereby privately held Ayala merged with Advaxis, with the combined company operating under the name Ayala Pharmaceuticals, Inc. and trading on Nasdaq under the ticker symbol AYLA. Roni Mamluk, Ph.D., continued as CEO of the combined company....more
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