Astex Pharmaceuticals is a biopharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for the treatment of cancer and diseases of the central nervous system. Utilizing its pioneering fragment-based drug discovery (FBDD) platform, Astex aims to deliver innovative medicines to patients with high unmet medical needs. The company operates as a wholly-owned subsidiary of Otsuka Pharmaceutical Co., Ltd., leveraging global resources and expertise.
Serves as the primary hub for drug discovery, research and development programs, and corporate leadership. It focuses on pioneering fragment-based drug discovery (FBDD) and early-stage clinical development.
State-of-the-art laboratories equipped for advanced drug discovery, including structural biology, biophysics, medicinal chemistry, and DMPK. Located within the prestigious Cambridge Science Park, fostering collaboration with academic and biotech entities.
A highly collaborative, science-driven environment that encourages innovation, critical thinking, and cutting-edge research. Employees often possess strong academic backgrounds and a shared passion for addressing unmet needs in oncology and CNS diseases.
Its location in Cambridge provides unparalleled access to a rich talent pool, leading academic institutions (including Cambridge University), and a vibrant biotech ecosystem, crucial for Astex's R&D innovation and pipeline progression. It underscores Astex's commitment to being at the forefront of pharmaceutical discovery.
Astex Pharmaceuticals supports its global drug discovery and development efforts primarily through its two main research and development hubs: Cambridge, UK, and Pleasanton, California, USA. These sites collaborate closely on a unified pipeline of novel therapeutics for oncology and diseases of the central nervous system, aiming to address global health challenges. As a wholly-owned subsidiary of Otsuka Pharmaceutical Co., Ltd., Astex benefits from Otsuka's extensive global network for later-stage clinical development, manufacturing, and commercialization, enabling its innovations to reach patients worldwide.
436 Cambridge Science Park, Milton Road
Cambridge
Cambridgeshire
United Kingdom
Address: 4140 Dublin Boulevard, Suite 200, Pleasanton, CA 94588, USA
To manage and execute clinical trials, engage with U.S. regulatory authorities like the FDA, support commercialization strategies, and conduct R&D activities complementary to the UK site, strengthening Astex's presence in the major U.S. pharmaceutical market.
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As of April 2025, Astex' leadership includes:
Astex has been backed by several prominent investors over the years, including:
Based on publicly available information and company announcements, there have been no major C-suite executive hires or departures publicly announced for Astex Pharmaceuticals in the last 12 months. The senior leadership team appears to be stable.
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Astex Pharmaceuticals likely utilizes standard corporate email formats. Common patterns include [first_initial][last] or [first].[last] followed by @astex.com. The exact internal convention may vary, but these are typical for companies of its nature.
[first_initial][last]@astex.com (e.g., jsmith@astex.com) or [first].[last]@astex.com (e.g., jane.smith@astex.com)
Format
hjhoti@astex.com
Example
85%
Success rate
astex.com • March 11, 2024
Astex Pharmaceuticals announced that the U.S. Food and Drug Administration (FDA) has approved a label update for INQOVI® (decitabine and cedazuridine) tablets. The update includes new data from a clinical study involving oral azacitidine (ONUREG®) in patients with Acute Myeloid Leukemia (AML), providing additional information for healthcare professionals....more
astex.com • February 20, 2024
Astex Pharmaceuticals and Cardiff University announced the extension of their strategic drug discovery collaboration. This long-standing partnership aims to leverage Astex's fragment-based drug discovery platform and Cardiff University's expertise in cancer research and neurodegeneration to develop new therapies for challenging diseases....more
Business Wire (via astex.com newsroom) • October 4, 2023
Astex Pharmaceuticals and Merck (known as MSD outside the U.S. and Canada) announced an expansion of their strategic oncology drug discovery collaboration. The collaboration focuses on identifying and developing small molecule candidates targeting a novel K-RAS oncogene pathway, leveraging Astex's fragment-based drug discovery platform....more
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