Apple Tree Partners (ATP) is a prominent venture capital firm specializing in the life sciences sector. Founded in 1999, ATP invests in and builds companies focused on developing breakthrough therapeutics, medical devices, and diagnostics. The firm is known for its deep scientific expertise, hands-on approach to company building, and a long-term commitment to fostering innovation that addresses significant unmet medical needs. ATP operates from key biotech hubs, creating and nurturing companies from inception to clinical impact and commercial success.
Serves as the central hub for ATP's global investment strategy, fund management, operational oversight, and leadership for its life sciences company-building activities.
Located in a prestigious Midtown Manhattan commercial building, offering modern office facilities and strategic access to New York's extensive financial and healthcare networks.
A dynamic, intellectually stimulating, and collaborative environment. The culture emphasizes scientific rigor, entrepreneurial spirit, and a results-driven approach to venture creation and investment in the life sciences.
The New York City headquarters positions ATP at the crossroads of global finance and burgeoning biotech innovation, facilitating critical connections with the investment community, research institutions, and pharmaceutical partners.
Apple Tree Partners maintains a significant global presence with key offices in major life sciences innovation hubs: New York (Global HQ), Cambridge (MA), San Francisco (CA) in North America, and London (UK) for its European operations. This strategic network enables ATP to identify, invest in, and build transformative life sciences companies worldwide, supporting global functions such as deal sourcing, due diligence, portfolio company management, and access to international talent and markets.
555 Fifth Avenue, 16th Floor
New York
NY
USA
Address: One Main Street, Suite 1320, Cambridge, MA 02142, USA
To leverage proximity to world-class academic institutions like MIT and Harvard, numerous research hospitals, and a high concentration of biotech startups and talent for deal flow and company building.
Address: 201 Spear Street, Suite 1100, San Francisco, CA 94105, USA
To tap into the vibrant West Coast life sciences community, including expertise in areas like genomics, digital health, and biopharmaceuticals, and to support ATP's investments in the region.
Address: The Post Building, Museum Street, London WC1A 1PB, United Kingdom
To expand ATP's global reach and access to cutting-edge science and entrepreneurial talent within Europe's diverse and growing biotech landscape, fostering transatlantic collaborations.
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As of April 2025, ATP (Apple Tree Partners)' leadership includes:
ATP (Apple Tree Partners) has been backed by several prominent investors over the years, including:
Over the past year (approx. May 2023 - May 2024), Apple Tree Partners notably strengthened its European presence with key senior appointments. No major high-level executive departures have been widely publicized, indicating stability in its core leadership team alongside strategic team expansions.
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Apple Tree Partners commonly uses the email format of the first initial of an employee's name followed by their full last name. Other formats might exist but this is the most frequently observed pattern.
flast@appletreepartners.com (e.g., jdoe@appletreepartners.com)
Format
sharrison@appletreepartners.com
Example
75%
Success rate
Apple Tree Partners Website / Business Wire • February 29, 2024
Chinook Therapeutics, a company incubated by ATP company ATPRx and focused on precision medicines for kidney diseases, was acquired by Novartis. The deal, valued at up to $3.5 billion, highlights a major success for ATP's investment and company-building strategy....more
Apple Tree Partners Website / PR Newswire • January 4, 2024
ATP announced the formation of Rapport Therapeutics, a new biopharmaceutical company dedicated to discovering and developing precision medicines for central nervous system (CNS) disorders. ATP led the $100 million Series A financing....more
Apple Tree Partners Website / Business Wire • May 8, 2023
ATP announced a significant expansion of its European operations, including the opening of a new office in London and the appointments of Kennen MacKay, M.D., Ph.D., as Managing Director, and Sam Hall, Ph.D., as Venture Partner for ATP Europe....more
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