Apellis Pharmaceuticals is a global biopharmaceutical company focused on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet medical need through inhibition of the complement cascade, a critical component of the immune system. The company is a leader in targeting C3, a central protein in this cascade, to develop transformative therapies for a broad range of debilitating conditions across ophthalmology, hematology, nephrology, and neurology.
Serves as the global corporate headquarters, housing executive leadership, research and development (R&D) laboratories, and key administrative functions that drive Apellis's overall strategy and operations.
Modern office and state-of-the-art laboratory spaces designed to foster scientific innovation and collaboration. Located within the dynamic Greater Boston biotechnology hub, offering access to a rich ecosystem of talent, research institutions, and industry partners.
Characterized by a strong emphasis on science, innovation, and a patient-centric mission. Apellis fosters a collaborative, fast-paced environment where employees are driven to develop breakthrough therapies for serious diseases.
The Waltham headquarters is pivotal for Apellis's R&D advancements, strategic decision-making, and global corporate governance. Its location in a prominent biotech cluster enhances talent recruitment, scientific collaborations, and industry engagement.
Apellis Pharmaceuticals maintains a significant global presence with key functions distributed across North America, Europe, and Australia. These functions include research and development, global manufacturing and supply chain management, clinical trial operations, commercial activities, medical affairs, and regulatory engagement. The company is strategically expanding its international footprint to deliver its C3-targeted therapies to patients with serious diseases worldwide.
100 Fifth Avenue
Waltham
Massachusetts
USA
Address: 4000 Apellis Way, Crestwood, KY 40014
Ensures the reliable manufacturing and supply of Apellis's therapies to meet patient needs globally, playing a key role in the company's operational backbone.
Address: Apellis Switzerland GmbH, Dammstrasse 21, CH-6300 Zug
Manages the launch, commercialization, and market access of Apellis's products across European countries and supports expansion into other international regions.
Address: Apellis Australia Pty Ltd, Level 36, Governor Phillip Tower, 1 Farrer Place, Sydney NSW 2000
Establishes and grows Apellis's presence in the Oceania region, ensuring patient access to its innovative treatments and engaging with local healthcare systems.
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As of April 2025, Apellis Pharmaceuticals' leadership includes:
Apellis Pharmaceuticals has been backed by several prominent investors over the years, including:
Over the past 12 months, Apellis Pharmaceuticals has made strategic appointments and transitions within its executive leadership to support its growth and commercial objectives. Key changes include the appointment of a new Chief Commercial Officer, a new Chief Medical Officer for Ophthalmology, and internal promotions to Chief Operating Officer and a newly created Chief Innovation Officer role.
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Apellis Pharmaceuticals typically uses a standard corporate email format. The most commonly observed pattern is `firstname.lastname@apellis.com`. Variations such as `firstinitiallastname@apellis.com` may also exist but are less frequent.
firstname.lastname@apellis.com
Format
john.smith@apellis.com
Example
85%
Success rate
Apellis Pharmaceuticals Investor Relations • May 7, 2024
Apellis reported $134.7 million in Q1 2024 total U.S. net product revenue for SYFOVRE® (pegcetacoplan injection). The company highlighted continued strong demand with over 62,000 commercial vials and 22,000 samples distributed in the quarter, and ongoing progress in market access for the geographic atrophy treatment....more
Apellis Pharmaceuticals Press Release • May 21, 2024
Apellis and Sobi announced that the Phase 3 VALIANT study of pegcetacoplan in adults with primary immune thrombocytopenia (ITP) met its primary endpoint. The study demonstrated a statistically significant improvement in platelet counts for patients treated with pegcetacoplan compared to placebo....more
Apellis Pharmaceuticals Press Release • January 3, 2024
Apellis outlined its strategic priorities for 2024, emphasizing maximizing the SYFOVRE® launch, advancing its C3 pipeline including APL-1030 for neurological diseases, and strengthening its financial foundation. The company also announced key leadership appointments and promotions to drive these initiatives....more
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