a2-biotherapeutics is a clinical-stage biotechnology company dedicated to pioneering the next generation of T-cell therapies for patients with solid tumors. Their proprietary Tmod™ (Target-activated T cell modality) platform is designed to create highly differentiated T cell therapeutics that can selectively target cancer cells while sparing normal cells. This logic-gated approach aims to address the critical challenge of on-target, off-tumor toxicity, potentially unlocking a broader range of tumor targets and improving patient outcomes in difficult-to-treat cancers.
Serves as the primary center for research and development, clinical operations, corporate strategy, and administrative functions. It houses state-of-the-art laboratories for cell therapy discovery and process development.
Modern laboratory facilities equipped for advanced cell engineering and analysis, collaborative workspaces designed to foster scientific innovation.
A fast-paced, science-driven environment characterized by collaboration, innovation, and a strong sense of mission to develop transformative cancer treatments. Employees are typically highly skilled and passionate about immuno-oncology.
The Agoura Hills headquarters is central to a2-biotherapeutics' ability to advance its Tmod™ platform from preclinical research through clinical development and potential commercialization.
While primarily based in the United States with its headquarters in California, a2-biotherapeutics's impact is global through its clinical trial operations, which may involve sites in multiple countries. Their research collaborations and potential future partnerships for drug development and commercialization could also extend their reach internationally as they advance their therapeutic pipeline.
29300 Agoura Rd
Agoura Hills
CA
USA
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As of April 2025, A2 Biotherapeutics, Inc.' leadership includes:
A2 Biotherapeutics, Inc. has been backed by several prominent investors over the years, including:
In the past 12-18 months, a2-biotherapeutics has strengthened its leadership team with key appointments, particularly in finance and legal roles, indicating a phase of growth and operational scaling.
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a2-biotherapeutics likely uses a standard corporate email format. Based on common practices in the biotechnology industry and similar-sized companies, the most probable format is the first initial followed by the last name.
flast@a2bio.com (e.g., jdoe@a2bio.com)
Format
sforaker@a2bio.com
Example
85%
Success rate
Business Wire • November 2, 2023
a2-biotherapeutics announced the appointment of Noah G. Berkowitz, M.D., Ph.D., as Chief Financial Officer. Dr. Berkowitz brings over 20 years of experience in healthcare finance, investment banking, and clinical medicine....more
GlobeNewswire • October 26, 2023
a2-biotherapeutics presented initial clinical data from its Phase 1 trial of A2B530 in patients with colorectal, pancreatic, and non-small cell lung cancers. The data showed a manageable safety profile and early signs of anti-tumor activity....more
Business Wire • June 1, 2023
a2-biotherapeutics announced the appointment of Sonja M. Nelson, J.D., Ph.D., as Chief Legal Officer and Corporate Secretary. Dr. Nelson has extensive experience in the life sciences industry, advising on legal, compliance, and corporate matters....more
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