645 Ventures
645 Ventures's Overview
645 Ventures is an early-stage venture capital firm that partners with exceptional founders building iconic companies in SaaS, infrastructure software, and consumer technology. They leverage a data-driven approach, their 'Prepared Mind' methodology, and a strong network to support entrepreneurs from seed to growth stages. The firm emphasizes collaboration, operational expertise, and a commitment to helping founders scale their businesses.
Where is 645 Ventures's Headquarters?
HQ Function
Serves as a primary hub for investment activities, portfolio company support, and networking within the East Coast tech ecosystem.
Notable Features:
Strategically located in a vibrant area of New York City, offering excellent accessibility and a dynamic environment conducive to venture capital operations.
Work Culture:
Fosters a collaborative, analytical, and results-driven environment, characteristic of early-stage technology investment firms. Emphasis is placed on deep research and strong founder relationships.
HQ Significance:
The New York headquarters anchors 645 Ventures in a major global financial and technology center, providing direct access to a rich pool of startups, talent, and co-investment opportunities.
Values Reflected in HQ: The choice of a New York City headquarters reflects the firm's commitment to being at the forefront of innovation, its dedication to rigorous market analysis, and its focus on building strong East Coast networks.
Location:
While primarily focused on investing in companies based in North America, particularly the United States, 645 Ventures supports portfolio companies with global aspirations. Their network and expertise assist founders in scaling their operations internationally and tapping into global markets. The firm seeks founders with ambitious, potentially global visions.
Street Address:
116 W Houston St, Floor 2
City:
New York
State/Province:
NY
Country:
USA
645 Ventures's Global Presence
San Francisco, CA/USA
Address: 1 Letterman Drive, Building C, Suite C3-700, San Francisco, CA 94129, USA
To identify and support promising early-stage companies in the Bay Area and broader West Coast technology landscape, and to provide a base for West Coast-based partners and operations.
Buying Intent Signals for 645 Ventures
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Executive Team of 645 Ventures
As of April 2025, 645 Ventures' leadership includes:
Investors of 645 Ventures
645 Ventures has been backed by several prominent investors over the years, including:
Executive New Hires/Exits in the Last 12 Months
In the past 12 months (May 2023 - May 2024), 645 Ventures has expanded its team with strategic hires in key operational roles such as Head of Platform and Venture Partner, enhancing its capabilities to support portfolio companies. No major Partner-level departures have been publicly announced during this period.
New Appointments:
Technology (Tech Stack) used by 645 Ventures
Discover the tools 645 Ventures uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.
645 Ventures Email Formats and Examples
645 Ventures primarily uses the [first]@645ventures.com email format for its employees. This is a common and straightforward pattern for professional communication within the venture capital industry.
[first]@645ventures.com (e.g., nnamdi@645ventures.com)
Format
aaron@645ventures.com
Example
90%
Success rate
News and media
Business Wire • July 25, 2023
645 Ventures Closes Over-Subscribed Early-Stage Funds IV and Select II, Totaling $347 Million in New Capital
645 Ventures announced the successful closing of two oversubscribed funds: Fund IV, dedicated to early-stage investments, and Select II, focused on growth-stage investments in existing portfolio companies. Together, these funds represent $347 million in new capital, significantly boosting the firm's assets under management and its capacity to support innovative founders....more
TechCrunch • October 24, 2023
645 Ventures Participates in $5M Seed Round for Donations Platform Overflow
645 Ventures participated in a $5 million seed funding round for Overflow, an innovative platform designed to help nonprofits and charities accept donations in the form of stocks and cryptocurrency. This investment underscores 645 Ventures' commitment to backing technology solutions that address unique market needs....more
645 Ventures Blog • July 19, 2023
645 Ventures Welcomes Julia French as New Head of Platform
645 Ventures announced the appointment of Julia French as its new Head of Platform. In her role, Julia French will be responsible for developing and scaling the resources, network, and operational support provided to the firm's rapidly growing portfolio of companies, thereby enhancing value creation across the fund....more
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