5am Ventures is a leading venture capital firm focused on building next-generation life science companies. Since its founding in 2002, 5am has invested in early-stage companies (Seed and Series A) that are working on groundbreaking research and development in areas such as biopharmaceuticals, new medicines, and advanced research. The firm actively partners with entrepreneurs to translate scientific discoveries into innovative therapies and solutions that can significantly impact patient lives. With a bi-coastal presence in the US, 5am Ventures leverages its deep scientific expertise and extensive network to support the growth and success of its portfolio companies.
Serves as a central hub for investment strategy, portfolio company management, fundraising, and West Coast operations.
Located in a prominent downtown business center, offering modern facilities conducive to collaboration, strategic meetings, and networking within the financial and biotech communities.
A dynamic, intellectually stimulating, and collaborative environment focused on scientific rigor, entrepreneurial spirit, and a commitment to advancing healthcare through innovation.
The San Francisco headquarters strategically positions 5am Ventures within the vibrant Bay Area life sciences ecosystem, providing direct access to world-class research institutions, talent, and emerging biotech companies.
While 5am Ventures' direct office presence is bi-coastal within the United States (San Francisco and Boston), its investment focus is primarily on North America. However, the firm actively monitors global scientific advancements and its portfolio companies often have global research, development, and commercialization strategies. 5am Ventures supports its companies in navigating international markets, forming global partnerships, and addressing worldwide health challenges.
One Embarcadero Center, Suite 2610
San Francisco
CA
USA
Address: 800 Boylston Street, Suite 1540, Boston, MA 02199
To actively participate in and contribute to the East Coast's world-leading life sciences ecosystem, fostering innovation and investments in therapeutics, diagnostics, and research tools.
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As of April 2025, 5AM Ventures' leadership includes:
5AM Ventures has been backed by several prominent investors over the years, including:
Over the last 12 months, 5am Ventures has significantly bolstered its leadership and scientific expertise through several key appointments and promotions, including a new General Counsel & CCO, a Chief Scientific Officer, and a new Venture Partner, alongside promoting existing team members to Partner. No major executive departures have been publicly announced during this period.
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5am Ventures typically utilizes an email format that combines the first initial of an employee's first name with their full last name, followed by '@5amventures.com'. This is a common and professional email structure in the venture capital industry.
[first_initial][last]@5amventures.com
Format
jdoe@5amventures.com
Example
75%
Success rate
PR Newswire • May 14, 2024
RayThera, a biotech company developing novel radiopharmaceuticals, announced an $18 million Series A financing. The round was co-led by 5AM Ventures and MRL Ventures Fund, with participation from other investors, to advance its pipeline of targeted alpha therapies....more
5am Ventures Website • January 11, 2024
5AM Ventures announced the promotions of Mira Chaurushiya, Ph.D., and Jamil M. Beg, Ph.D., M.B.A., to Partner, and the additions of David Allison, Ph.D., as Venture Partner, and Meron Mengistu, Ph.D., as Chief Scientific Officer, strengthening its investment and scientific teams....more
5am Ventures Website • March 2, 2023
5AM Ventures announced the closing of $750 million in new capital, comprising the $450 million 5AM Ventures VII, L.P. fund for early-stage investments and the $300 million 5AM Opportunities II, L.P. fund for later-stage and public company investments, to continue backing transformative life science companies....more
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