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21GRAMS's Overview

Total employees447
HeadquartersNew York
Founded

21GRAMS is an award-winning, global advertising agency dedicated to making healthcare and pharmaceutical brands more human and relatable. They focus on creating impactful campaigns that resonate deeply with both patients and healthcare professionals. As part of Real Chemistry, 21GRAMS leverages data analytics and creative storytelling to address complex health challenges and improve patient outcomes. Their work spans a wide range of therapeutic areas and communication channels, emphasizing authenticity and emotional connection under the philosophy 'Make Science Human'.

Where is 21GRAMS's Headquarters?

21GRAMS office21GRAMS office21GRAMS office21GRAMS office
*Images sourced via web search. Rights belong to original owners

HQ Function

Serves as a primary operational hub for 21GRAMS' creative, strategic, and client service teams, focusing on health advertising and benefiting from New York's dynamic media and advertising ecosystem.

Notable Features:

Located in a modern office building in a prominent New York City business district, offering collaborative workspaces designed to foster creativity and innovation for its advertising and marketing teams within the Real Chemistry infrastructure.

Work Culture:

Characterized by a fast-paced, creative, and highly collaborative environment. The culture is deeply rooted in the 'Make Science Human' philosophy, emphasizing empathy, purpose-driven work, and innovation in health communications. As part of Real Chemistry, it shares a commitment to data-driven insights and integrated solutions.

HQ Significance:

The New York City presence is strategically important for 21GRAMS, providing access to a rich pool of advertising and creative talent, proximity to major pharmaceutical and healthcare clients, and keeping the agency at the forefront of communication and advertising trends.

Values Reflected in HQ: The New York operational hub reflects values of creativity, collaboration, innovation, and a profound commitment to making a positive impact in the health sector, aligning with Real Chemistry's broader mission and 21GRAMS's unique brand identity.

Location:

As an integral part of Real Chemistry, 21GRAMS leverages a robust global network to serve clients worldwide. While its core creative and strategic teams are prominent in North America (especially New York and San Francisco) and Europe (London), its capabilities extend across Real Chemistry's international offices. This global footprint enables 21GRAMS to develop and execute culturally relevant and compliant advertising campaigns, provide strategic insights, and deliver medical communications for multinational pharmaceutical and healthcare companies across diverse markets.

Street Address:

200 Vesey Street, 24th Floor

City:

New York

State/Province:

NY

Country:

USA

21GRAMS's Global Presence

San Francisco, CA/USA

Address: 401 Castro Street, San Francisco, CA 94114

Key hub for West Coast operations, connecting 21GRAMS with the biotech, pharmaceutical, and technology industries prevalent in the Bay Area, fostering innovation in health communications.

London, UK

Address: The Bindery, 51-53 Hatton Garden, London, EC1N 8HN, UK

Supports European and international clients by providing localized marketing, advertising, and communication strategies within the complex European healthcare landscape.

Chicago, IL/USA

Address: 222 W Merchandise Mart Plaza, Suite 1212, Chicago, IL 60654

Provides strategic access to clients and talent in the central United States, focusing on health and wellness brands based in the Midwest and enhancing national campaign reach.

Buying Intent Signals for 21GRAMS

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Executive Team of 21GRAMS

As of April 2025, 21GRAMS' leadership includes:

Frank X. Mazzola - Co-Founder & President, 21GRAMS at Real Chemistry
Robert Blink - Co-Founder & Managing Partner, Creative, 21GRAMS at Real Chemistry
Tom Richards - Co-Founder & Chief Creative Officer, 21GRAMS at Real Chemistry
Wendy Levine - Managing Partner, Client Services, 21GRAMS at Real Chemistry
Jemma Boyle - Managing Director, 21GRAMS London at Real Chemistry

Investors of 21GRAMS

21GRAMS has been backed by several prominent investors over the years, including:

New Mountain Capital (via parent company Real Chemistry)

Executive New Hires/Exits in the Last 12 Months

Hire0
Exits0

No major publicly announced executive hires or exits specifically for the 21GRAMS brand leadership team have been prominently featured in industry news over the last 12 months. Leadership changes are typically integrated within broader Real Chemistry announcements or internal promotions.

Technology (Tech Stack) used by 21GRAMS

Discover the tools 21GRAMS uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

21GRAMS Email Formats and Examples

As 21GRAMS is part of Real Chemistry, employees use Real Chemistry email addresses. The most common email format observed for Real Chemistry is the first initial followed by the last name.

[first_initial][last]@realchemistry.com

Format

jdoe@realchemistry.com (example for Jane Doe)

Example

85%

Success rate

News and media

PR NewswireSeptember 15, 2023

21GRAMS Named Clio Health Agency of the Year for Second Consecutive Year

21GRAMS, part of Real Chemistry, was awarded the prestigious Agency of the Year title at the 2023 Clio Health Awards, marking its second consecutive win. This recognition highlights their continued excellence in creating innovative and impactful health advertising campaigns....more

MM+M Online (Medical Marketing and Media)June 8, 2023

MM+M Agency 100 2023 Profile: 21GRAMS

21GRAMS was featured in the MM+M Agency 100 list for 2023, recognized for its significant revenue growth and impactful work in health advertising. The profile highlighted its 'Make Science Human' philosophy and key campaigns contributing to its success....more

Ad AgeMarch 30, 2023

21GRAMS and Arnold Worldwide Collaborate on 'The Messenger' Campaign for National Kidney Foundation

21GRAMS, in partnership with Arnold Worldwide, launched 'The Messenger' campaign for the National Kidney Foundation. The campaign aimed to raise awareness about kidney disease, particularly within Black communities, utilizing powerful storytelling to encourage early detection and testing....more

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